TORONTO -- Children with HIV infection reported experiencing more pain--and for longer durations--than did their uninfected counterparts in a large, prospective, multicenter observational study.
The study included 576 children, aged 6-18 years, 320 of whom had perinatal HIV infection and 256 of whom were HIV-uninfected siblings or children living in a household with a person who was HIV positive.
Pain prevalence was significantly higher in HIV-positive children than in HIV-negative children within the last 2 months (41% vs. 32%) and within the last 2 weeks (28% vs. 19%) before completion of the study questionnaire, reported Dr. Sharon Nachman on behalf of the Pediatric AIDS Clinical Trials Group 1055.
Pain was also reported as lasting longer than 1 week in 20% of HIV-positive children, compared with 11% of HIV-negative children.
The high prevalence of pain in children without HIV infection may reflect economic and family stresses, Dr. Nachman, professor of pediatrics and director of pediatric infectious diseases, at Stony Brook (N.Y.) University Medical Center, said during a poster presentation at the annual meeting of the Pediatric Academic Societies.
Uninfected children were significantly more likely to live with a biologic parent, but those households had lower annual incomes and lower primary-caregiver education levels, Dr. …