MRS Pretty and the Voluntary Euthanasia Society yesterday launched a website featuring an on-line petition supporting the right to assisted suicide.
Mr Pretty called on the British people to put pressure on the Government to change the law.
"We hope the people will sign on Diane's behalf asking the Government to do something about the law to allow her to have her right to choose the way she dies.
"If the British people are behind Diane then it will be a great help."
He said that no doctors had approached them to offer Mrs Pretty help in achieving assisted suicide, and pointed out that moving to another European country where assisted suicide was legal would not help his wife because she would have to be resident for three years.
The last time she saw her doctors they told her that her life expectancy was "limited to months", he added.
He said they did not expect to mount an appeal against the European decision.
"I think she has finally decided that this is enough," he said.
"If it goes the way it's gone already she will only be disappointed."
Refusing medication was not an option for his wife either, he said, because the drugs she was taking control her pain rather than keep the disease in check.
He added: "Diane has never regretted taking it on.
"It's taken its toll on me, but Diane has never regretted doing it.
"She has got very good palliative care. I'm at home 24 hours a day and I am at her beck and call.
"When she is on respite care she has nurses at her beck and call. …