ALDOSTERONE

ălˌdōstĭrōnˈ, steroid secreted by the cortex of the adrenal gland. It is the most potent hormone regulating the body's electrolyte balance. Aldosterone acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water), and to increase the rate of potassium-ion excretion. The secretion of aldosterone appears to be regulated by two mechanisms. First, the concentration of sodium ions may be a factor since increased rates of aldosterone secretion are found when dietary sodium is severely limited. Second, reduced blood flow to the kidney stimulates certain kidney cells to secrete the proteolytic enzyme renin, which converts the inactive angiotensinogen globulin in the blood into angiotensin I. Another enzyme then converts angiotensin I into angiotensin II, its active form. This peptide, in turn, stimulates the secretion of aldosterone by the adrenal cortex. Pathologically elevated aldosterone secretion with concomitant excessive retention of salt and water often results in edema.

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The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

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Questia Books and Articles on: Aldosterone
We found: 158 results
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books on: Aldosterone  - 106 results

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1.
Animal Hormones: A Comparative Survey - Vol. 1
Book by Penelope M. Jenkin, John E. Harris; Pergamon Press, 1962
Subjects: Hormones
...M 5.211 " " " " " M 5.223 " " " " " M 5.412 " " " " " M 5.421 " " " Aldosterone-like M 5.311 " " " Hydrocortisone-like M 5.321 * M = metabolic. respond to stimulation by the adrenocorticotrophic...
2.
Hypertension in Diabetes
Book by Bryan Williams; Martin Dunitz, 2003
Subjects: Hypertension
...extracellular sodium and the renin angiotensin aldosterone system Exchangeable sodium is frequently...or normal or Aldosterone normal or normal or...Plasma angiotensin II (Ang II) and aldosterone are generally normal or suppressed in...
3.
Hurst's the Heart: Manual of Cardiology
Book by Robert A. O'Rourke, Valentin Fuster, R. Wayne Alexander, Robert Roberts, Spencer B. King III, Hein J. J. Wellens; McGraw-Hill, 2001
Subjects: Cardiovascular System--Diseases, Heart--Diseases
...that beta- blocker therapy as well as aldosterone inhibitors reduce morbidity and mortality...the sympathetic and renin-angiotensin-aldosterone sys- tem (RAAS) occurs at some variable...in renal vasoconstriction, increased aldosterone secretion, sodium accumulation, and...
4.
Conquering High Blood Pressure: The Complete Guide to Managing Hypertension
Book by Stephen Wood M. D., Bert P. A. Griffith; Perseus Books, 1997
Subjects: Hypertension--Popular Works
...adrenal glands to secrete the hormone aldosterone . The convoluted relationship between...referred to as the renin-angiotensin-aldosterone system. Another hormone that regulates...excessive production of a hormone known as aldosterone. In primary cases, which are very rare...
5.
Heart Disease in Women
Book by Susan Wilansky, James T. Willerson; Churchill Livingstone, 2002
Subjects: Heart Diseases In Women
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journal articles on: Aldosterone  - 20 results

       More journal Results: 1-10 11-20 >>  
 
1.
Irreversible Binding and Adrenocorticolytic Activity of the DDT Metabolite 3-Methylsulfonyl-DDE Examined in Tissue-Slice Culture
Journal article by Orjan Lindhe, Bert-Ove Lund, Ake Bergman, Ingvar Brandt; Environmental Health Perspectives, Vol. 109, 2001
...Corticosterone, 11-deoxycorticosterone, and aldosterone concentrations in the medium were measured...that in nontreated slices (Figure 2). Aldosterone content increased almost 4-fold (p is...increase (p is less than 0.01), while aldosterone secretion was more than halved (p is...
2.
Organotins Disrupt the 11[beta]-Hydroxysteroid Dehydrogenase Type 2-Dependent Local Inactivation of Glucocorticoids
Journal article by Atanas G. Atanasov, Lyubomir G. Nashev, Steven Tam, Michael E. Baker, Alex Odermatt; Environmental Health Perspectives, Vol. 113, 2005
...USA). The recently described RCCD-2 aldosterone-sensitive rat cortical collecting duct...translocation by vasopressin of the aldosterone-induced pool of latent Na-K-ATPases...subunit dephosphorylation: study in a new aldosterone-sensitive rat cortical collecting duct...
3.
Pollutant Particles Produce Vasoconstriction and Enhance MAPK Signaling Via Angiotensin Type 1 Receptor
Journal article by Zhuowei Li, Jacqueline D. Carter, Lisa A. Dailey, Yuh-Chin T. Huang; Environmental Health Perspectives, Vol. 113, 2005
Subjects: Air pollution
...such as vasoconstrictor hormones, growth factors, cytokines, aldosterone, and extracellular matrix components (Jacoby and Rader 2003...From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension...
4.
Biofeedback Relaxation Training: a Rediscovered Mind-body Tool in Public Health
Journal article by Kristine S. Calderon, Winifred W. Thompson; American Journal of Health Studies, Vol. 19, 2004
Subjects: Biofeedback, Clinical trials, Health behavior, Mind body relationship, Nervous system, Public health, Responses, Stress
...adrenocorticotropic hormone (ACTH) from the anterior pituitary gland stimulates the adrenal cortex to release aldosterone and cortisol. Aldosterone increases sodium and water retention by the kidney. Cortisol, in cooperation with catecholamines, increases...
5.
Alcoholic Lung Disease
Journal article by Corey D. Kershaw, David M. Guidot; Alcohol Research & Health, Vol. 31, 2008
Subjects: Acute respiratory distress syndrome--Care and treatment, Acute respiratory distress syndrome--Diagnosis, Acute respiratory distress syndrome--Research, Acute respiratory distress syndrome--Risk factors, Adult respiratory distress syndrome--Care and treatment, Adult respiratory distress syndrome--Diagnosis, Adult respiratory distress syndrome--Research, Adult respiratory distress syndrome--Risk factors, Alcoholism--Complications and side effects, Alcoholism--Research, Bacterial pneumonia--Care and treatment, Bacterial pneumonia--Diagnosis, Bacterial pneumonia--Research, Bacterial pneumonia--Risk factors, Pneumonia--Care and treatment, Pneumonia--Diagnosis, Pneumonia--Research, Pneumonia--Risk factors
...2307395 LINKOLA, J.; FYHRQUIST, F.; AND YLIKHARI, R. Renin, aldosterone, and cortisol during ethanol intoxication and hangover. Acta...N.N.; ET AL. Chronic ethanol ingestion modifies the renin-aldosterone axis independent of alterations in the regulation of atria...
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magazine articles on: Aldosterone  - 8 results

       More magazine Results: 1-8 >>  
 
1.
Steroid Action Gets a Rewrite
Magazine article by Mark Greener; The Scientist, Vol. 17, September 8, 2003
...within five minutes of injecting aldosterone, a mineralocorticoid.1 This response...too quick for transcription. Aldosterone also rapidly changes sodium exchange...recently that the rat brain produces aldosterone and corticosterone (the rat equivalent...
2.
Latest Research
Magazine article; Medical Economics, Vol. 84, October 19, 2007
...events, according to Canadian researchers. They suggest that increased activation of the sympathetic and the renin-angiotensin-aldosterone systems contributes to inflammation of the arterial wall and subsequently to the formation of thrombosis. Topiramate Shows...
3.
Top 10 Laboratory Tests: Blood Will Tell
Magazine article by Dixie Farley; FDA Consumer, Vol. 23, July 1989
Subjects: Blood tests--Medical examination, Blood--Medical examination, Diagnosis, Laboratory--Evaluation, Laboratory diagnosis--Evaluation
...adrenal gland secretes less of the hormone aldosterone, and that causes the kidneys to step...process is reversed: Elevated secretion of aldosterone causes the kidneys to reabsorb sodium...concentration also can indicate insufficient aldosterone. An abnormally low sodium level generally...
4.
Latest Research
Magazine article; Medical Economics, Vol. 85, December 19, 2008
...has been adversely linked to cardiovascular health, possibly because vitamin D deficiency activates the reninangiotensin-aldosterone system. * No Link Seen Between Meat and Small Intestinal Cancer Cancer Res. 2008;68:9274-9279. November 15, 2008 Consumption...
5.
Genesis Meets the Big Bang and Evolution, Absent Design
Magazine article by Laura E. Bothwell; Cross Currents, Vol. 57, Spring 2007
Subjects: Human evolution--Analysis, Natural selection--Analysis, Religion and science--Analysis
...molecular system--the functional interaction of the hormone aldosterone and its partner receptor (the mineralocorticoid receptor...By procuring and examining ancestral genes to the hormone aldosterone, scientists showed that long before the hormone itself had...
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newspaper articles on: Aldosterone  - 13 results

       More newspaper Results: 1-10 11-13 >>  
 
1.
Evolutionary Biologists Score One for Darwin
Newspaper article; The Register-Guard (Eugene, OR), April 7, 2006
...the receptor protein for the hormone aldosterone, which regulates the bodys salt balance...evolutionary link when he put modern-day aldosterone in with its resurrected ancestral receptor...by millions of years. "Its as good an aldosterone receptor as the present-day human aldosterone...
2.
How High Blood-Pressure May Be a Problem You Are Born With
Newspaper article; The Daily Mail (London, England), May 16, 2009
Subjects: Hypertension
...system for regulating a hormone called aldosterone is established in the womb. Dr Rebecca...that the mechanisms which set up how aldosterone is regulated start in early life. Aldostrone...tests carried out to analyse levels of aldosterone and how it was regulated. They suggested...
3.
Keeping It Real
Newspaper article; The Register-Guard (Eugene, OR), April 12, 2006
...re-create the ancestor of the receptor protein for the hormone aldosterone, which regulates the bodys salt balance. The UO scientists...relationship still worked perfectly when he put modern-day aldosterone with the re-created ancient receptor. Thorntons research...
4.
Gathering Helps Lifts Awareness
Newspaper article; The Chronicle (Toowoomba, Australia), July 16, 2009
...affecting between one to five people per 100,000 people. It is caused when the adrenal gland ceases to produce cortisol and aldosterone, two important hormones. Symptoms include severe fatigue, weakness, recurring illness, nausea, abdominal pain, loss of weight...
5.
Everyone Requires Some Salt in Diet
Newspaper article; The Washington Times, April 10, 2005
...can be harmful. Severe salt restriction causes high blood pressure by making the adrenal glands release large amounts of aldosterone and the kidneys to release renin. Both hormones constrict arteries to cause high blood pressure. People on salt-wasting diuretics...
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encyclopedia articles on: Aldosterone  - 11 results

       More encyclopedia Results: 1-10 11-11 >>  
 
1.
Aldosterone
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
ALDOSTERONE al dostiron , steroid secreted by the cortex of the...hormone regulating the bodys electrolyte balance. Aldosterone acts directly on the kidney to decrease the rate of...the rate of potassium-ion excretion. The secretion of aldosterone appears to be regulated by two mechanisms. First, the...
2.
Adrenal Gland
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
...about 30 steroid hormones, the most important of which are aldosterone and cortisol . Cortisol regulates carbohydrate, protein...adrenocorticotropic hormone (ACTH) from the pituitary gland. Aldosterone regulates water and salt balance in the body; its secretion...
3.
Corticosterone
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
...humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone , another adrenal cortical steroid. ____________________ Copyright 2009 Columbia University Press. Used with the permission...
4.
Cortisone
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
...diabetes in sufficiently high doses. Cortisone also exerts an effect on salt retention in the kidneys similar to that of aldosterone , although it is not as potent. The hormone causes increased breakdown of proteins and decreased protein synthesis, and large...
5.
Cholesterol
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
...precursor for the synthesis of vitamin D3, of the various steroid hormones , including cortisol , cortisone , and aldosterone in the adrenal glands , and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol is excreted from...
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