CYTOCHROME

sīˈtəkrōmˌ, protein containing heme (see coenzyme) that participates in the phase of biochemical respiration called oxidative phosphorylation. Cytochromes act as carriers of hydride ions (sometimes considered to be the equivalent of electron pairs) in the series of complex enzymes known as the electron transport chain. As the hydride ions or their equivalent travel along the electron transport chain, each cytochrome is in turn reduced (accepts a hydride ion or pair of electrons) and then oxidized (donates the hydride ion or pair of electrons to the next acceptor in the chain); in the process the iron atom in the cytochrome heme shuttles between the ferrous and ferric states. The cytochromes were discovered in 1886.

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The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

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Questia Books and Articles on: Cytochrome
We found: 1040 results
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books on: Cytochrome  - 246 results

       More book Results: 1-10 11-20 21-30 31-40 41-50 >>  
 
1.
General Cytology
Book by E. D. P. De Robertis; W. B. Saunders, 1960
Subjects: Cytology
Each of the cytochromes has different properties. Cytochrome c combines with carbon monoxide...bacteria that do not possess cytochrome was discovered, cytochromes were found, a1 and a2. In 1939, another cytochrome was discovered, cytochrome...
2.
Manometric Techniques: A Manual Describing Methods Applicable to the Study of Tissue Metabolism
Book by W. W. Umbreit, R. H. Burris, J. F. Stauffer; Burgess Pub. Co., 1957
Subjects: Tissue Metabolism
...protein which can be removed to yield cytochrome with an apparent molecular weight of...example, one adds 4 O 10-8 moles of cytochrome c per Warburg flask, which is therefore...from six beef hearts thus gives enough cytochrome for about 1000 Warburg flasks when the...
3.
A Symposium on Light and Life
Book by William D. McElroy, Bentley Glass; Johns Hopkins Press, 1961
Subjects: Photobiology--Congresses
...exclusively to the cytochromes of higher plant...higher plants that a cytochrome, localized in...this component cytochrome b 6 . Some of the characteristics of cytochromes f and b 6 are given in Table 1 . Cytochrome f is the only chloroplast...
4.
Subcellular Particles: A Symposium Held during the Meeting of the Society of General Physiologists at the Marine Biological Laboratory, Woods Hole, Massachusetts, June 9-11, 1958
Book by Teru Hayashi; Ronald Press Co., 1959
Subjects: Cytology
this cytochrome from both yeast and heart muscle. The isolated cytochrome is a water-soluble molecule...soluble forms in which the cytochromes and the flavoproteins can...best of our knowledge, cytochrome c in its classical form...
5.
Hormones, Genes, and Cancer
Book by Brian E. Henderson, Bruce Ponder, Ronald K. Ross; Oxford University Press, 2003
Subjects: Cancer--Endocrine Aspects, Generative Organs--Cancer--Chemoprevention, Generative Organs--Cancer--Molecular Aspects, Hormones--Carcinogenicity
...sis of two common human cytochrome P4501B 1 variants. Arch...Contribution of human hepatic cytochrome P450 isoforms to re- gioselective...HH, Berthou F. Nature of cytochromes P450 involved in the 2...variations in hu- man liver cytochrome P-450 enzymes involved...
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journal articles on: Cytochrome  - 621 results

       More journal Results: 1-10 11-20 21-30 31-40 41-50 >>  
 
1.
Alcohol Metabolism's Damaging Effects on the Cell: A Focus on Reactive Oxygen Generation by the Enzyme Cytochrome P450 2E1
Journal article by Dennis R. Koop; Alcohol Research & Health, Vol. 29, 2006
Subjects: Acetaldehyde--Physiological aspects, Alcohols--Physiological aspects, Alternative fuels--Physiological aspects, Cytochrome P-450--Physiological aspects, Liver diseases--Physiological aspects, Mitochondrial DNA--Physiological aspects, Oxides--Physiological aspects, Radicals (Chemistry)--Physiological aspects
...oxidation pathway involving cytochrome P450 is present predominately...proteins, such as the cytochromes of the electron transport...GONZALEZ, F.J. Role of cytochromes P450 in chemical toxicity...GUENCERICH, F.P. Cytochromes P450, drugs, and...GUENGERICH, F.P. Cytochrome P450s and other enzymes...
2.
Cbt1 Interacts Genetically with Cbp1 and the Mitochondrially Encoded Cytochrome B Gene and Is Required to Stabilize the Mature Cytochrome B Mrna of Saccharomyces Cerevisiae
Journal article by Timothy P. Ellis, Melissa S. Schonauer, Carol L. Dieckmann; Genetics, Vol. 171, 2005
Subjects: CBT1 protein, S cerevisiae, Cytochromes b, DNA polymerase, Genes, Microbiology, Mitochondrial DNA, Mutation, RNA, Fungal, RNA, Messenger, RNA, Ribosomal, Retroelements, Saccharomyces cerevisiae Proteins, cbp1 protein, S cerevisiae
...Cbp1 and the Mitochondrially Encoded Cytochrome B Gene and Is Required to Stabilize the Mature Cytochrome B Mrna of Saccharomyces Cerevisiae by...for stabilization of mitochondria! cytochrome b (COB) RNAs (UIECKMANN et al. 1982...
3.
Alcohol Metabolism's Damaging Effects on the Cell: a Focus on Reactive Oxygen Generation by the Enzyme Cytochrome P450 2e1
Journal article by Dennis R. Koop; Alcohol Research and Health, Vol. 29, 2006
Subjects: Cells, Cytochrome P-450 CYP2E1, Electrons, Enzymes, Ethanol, Free radicals, Liver diseases, Molecules, Proteins, Reactive Oxygen Species, Superoxides
...in the liver by the enzyme cytochrome P450 2E1 (CYP2E1) and the...at the terminal enzyme (cytochrome oxidase) of that chain...oxidation pathway involving cytochrome P450 is present predominately...containing proteins, such as the cytochromes of the electron transport...
4.
C-type Cytochrome Assembly in Saccharomyces Cerevisiae: a Key Residue for Apocytochrome C^sub 1^/lyase Interaction
Journal article by Vincent Corvest, Darren A. Murrey, Delphine G. Bernard, David B. Knaff, Bernard Guiard, Patrice P. Hamel; Genetics, Vol. 186, 2010
Subjects: Binding sites, Chemical bonds, Enzymes, Mutation
...THE c-type cytochromes, also referred to as cytochrome c, represent...two c-type cytochromes, the soluble cytochrome c and the membrane...ofmitochondrial c-type cytochromes (Bernard et...for c-type cytochrome maturation but...
5.
Occupational Toluene Exposure Induces Cytochrome P450 2E1 mRNA Expression in Peripheral Lymphocytes
Journal article by Ania Mendoza-Cantu, Fabiola Castorena-Torres, Mario Bermudez De Leon, Bulmaro Cisneros, Lizbeth Lopez-Carrillo, Aurora E. Rojas-Garcia, Alberto Aguilar-Salinas, Maurizio Manno, Arnulfo Albores; Environmental Health Perspectives, Vol. 114, 2006
Subjects: Messenger RNA
...for indirect evaluation of cytochrome P4502E1 activity in humans...Manno M, Berthou F. 2001. Cytochrome CYP2E1 phenotyping and genotyping...frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in...RS. 1994. Induction of cytochrome P450 by toluene. Int J Biochem...
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magazine articles on: Cytochrome  - 159 results

       More magazine Results: 1-10 11-20 21-30 31-40 41-50 >>  
 
1.
Mitochondria at the Crossroads of Life and Death
Magazine article by Amy Adams; The Scientist, Vol. 18, October 11, 2004
...Southwest Medical Center in Dallas described cytochrome c release from the mitochondria as an...initially skeptical, Wang recalls. Cytochrome c was well known as an electron-shuttling...Bcl-2 blocks apoptosis by preventing cytochrome c release from the mitochondria. Further...
2.
New Drugs of 1993: Part 1
Magazine article by Ronald F. Borne, Michael C. Vinson; Drug Topics, Vol. 138, February 7, 1994
Subjects: Alcon Laboratories Inc, Carter-Wallace Inc, Continuing education, Forest Laboratories Inc, Manycompanies, Manyproducts, Ortho Biotech Inc, Pharmacists, Prescription drugs, Product introduction, Schering-Plough Corp, Statistical data, United States
...INTERACTION POTENTIAL: As an inducer of the cytochrome P-450 system, felbamate increases...Other medications metabolized by the cytochrome P-450 system may also demonstrate...in combination with inhibitors of the cytochrome P-450 system. Felbamate has been...
3.
New Drug Approvals of 1998 - Part 2
Magazine article by W. Marvin Davis, I. Wade Waters; Drug Topics, Vol. 143, March 1, 1999
Subjects: Alcon Laboratories Inc, Astra Merck Inc, COR Therapeutics Inc, Cephalon Inc, FDA approval, Glaxo Wellcome Inc, Manycompanies, Manyproducts, Pharmaceutical industry, Prescription drugs, Product introduction, United States
...microsomes, abacavir showed no inhibition of cytochrome P450 enzymes (2C9, 2D6, 3A4), which...in the gastrointestinal tract, the cytochrome P450 system is not influenced by the...Celecoxib metabolism is mediated mainly by cytochrome P450 2C9 in the liver. Thus, coadministration...
4.
The Class of 1997--part 1: Make Way for 39 New Drug Approvals
Magazine article by Michael C. Vinson, W. Marvin Davis, I. Wade Waters; Drug Topics, Vol. 142, February 2, 1998
Subjects: Bayer Corp, Continuing education, Drugs, FDA approval, Manycompanies, Manyproducts, Neurex Corp, Novartis, Pharmacia & Upjohn, Pharmacists, United States, Wyeth-Ayerst Laboratories
...binding to the heme group of aromatase, a cytochrome P-450 enzyme that is responsible for...since letrozole is known to inhibit some cytochrome P-450 enzymes. Adverse reactions...terfenadine. The drug is an inhibitor of cytochrome P-450 2D6, 3A4, and 1A2. Its administration...
5.
How to Detect Apoptosis
Magazine article by Jeffrey M. Perkel; The Scientist, Vol. 20, April 2006
...Pharmingen, $325 for 200 assays 4 Cytochrome c release assays During apoptosis the...mitochondrial membrane ruptures, releasing cytochrome c, while leaving the inner membrane...fail, so Reed recommends combining cytochrome c and inner membrane integrity tests...
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newspaper articles on: Cytochrome  - 13 results

       More newspaper Results: 1-10 11-13 >>  
 
1.
Kilbane Looking to Lift Cyp Curse; REP OF IRELAND V CYPRUS GROUP EIGHT, WEDNESDAY, KICK-OFF 7.45pm
Newspaper article; Sunday Mirror (London, England), October 12, 2008
Subjects: Cytochrome P-450
2.
Kilbane Looking to Lift Cyp Curse; REP OF IRELAND V CYPRUS GROUP EIGHT, WEDNESDAY KICK-OFF 7.45pm
Newspaper article; Sunday Mirror (London, England), October 12, 2008
Subjects: Cytochrome P-450
3.
Breathe through Your Mouth
Newspaper article; The Washington Times, August 10, 2003
...drugs are broken down in your intestines by an enzyme called cytochrome P450 that is normally there, so these drugs have to be given...levels. Grapefruit juice contains bergamottin that blocks cytochrome P450, so that these drugs are not broken down and much higher...
4.
Swallowed by a Big Cat; ANSWERS TO CORRESPONDENTS
Newspaper article; The Daily Mail (London, England), January 16, 2007
...certain drugs, because it is metabolised in the liver by the cytochrome P450 3A4 enzyme, the same enzyme that breaks the drugs down. The grapefruit juice can overload the system, blocking the cytochrome P450 pathway, and the levels of these drugs become elevated...
5.
Running, Jumping Increase Back Pain
Newspaper article; The Washington Times, December 24, 2006
Subjects: Back pain, Backache
...drugs are broken down in your intestines by an enzyme called cytochrome P450 that is normally there, so these drugs have to be given...levels. Grapefruit juice contains bergamottin that blocks cytochrome P450, so that these drugs are not broken down and much higher...
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encyclopedia articles on: Cytochrome  - 1 result

 
 
1.
Cytochrome
Encyclopedia article; The Columbia Encyclopedia, Sixth Edition, 2009
CYTOCHROME si t krom , protein...phosphorylation . Cytochromes act as carriers...transport chain, each cytochrome is in turn reduced...iron atom in the cytochrome heme shuttles between...ferric states. The cytochromes were discovered...


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