ERGOT

ûrˈgət, disease of rye and other cereals caused by the fungus Claviceps purpurea. The cottony, matlike body, or mycelium, of the fungus develops in the ovaries of the host plant; it eventually turns into a hard pink or purple body, the sclerotium, or ergot, that resembles a grain of rye in shape. The sclerotium contains alkaloids (many of which are biologically active) that are toxic to humans and livestock. Ergot poisoning, or ergotism, epidemic in the Middle Ages, results from eating bread made of rye contaminated with ergot. Ergot poisoning is characterized by constriction of blood vessels, resulting in numbness and the development of gangrene in extremities; it may also affect the nervous system. Some of the alkaloids in ergot, e.g., ergotamine and ergonovine, are used as medicines; these alkaloids are chemical derivatives of lysergic acid, which is used in the synthesis of the hallucinogen LSD. Ergotamine alleviates migraine headaches. Ergonovine is used medicinally to stop hemorrhage and cause contraction of the uterus; during the 17th cent. midwives used ergot to stop postpartum uterine bleeding.

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The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

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Questia Books and Articles on: Ergot
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books on: Ergot  - 289 results

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ERGOCRISTINE See Ergot. ERGOCRISTININE See Ergot. ERGOMETRINE See Ergot. ERGOMETRININE See Ergot. ERGOMONAMINE See Ergot. ERGONOVINE Ergometrine. See Ergot. ERGOSINE See Ergot. ERGOSINNINE See Ergot. ERGOSTEROL C 28 H 44 O; m.p. 163...
...to be any written accounts of the use of ergot for medicinal pur- poses during the Middle...of its properties were known earlier. Ergot poisoning was recog- nized, and there are reports of seizures caused by consuming ergot. Epidemics caused by ergot poisoning were...
...several hallucinogenic chemicals called ergot alkaloids, C>f these psychoactive aikatoKis...which are closely related t`> I.SD. Ergot all;aloids naturally occur in several...the beginning of the twentieth centtn\. Ergot t illol,c commonly known as ergot, is...
Ergot Ergot is a fungus that grows on crops like rye, wheat, oats, and barley and can be recognized as a black growth (ergot is French for rooster spur). The fungus, of which Claviceps purpurea...
...individuals at once. Rye is particularly susceptible to ergot contamination. Cold and damp growing or storage conditions also promote the formation of ergot. Ergot is the source of lysergic acid diethylamide LSD ; it and...
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journal articles on: Ergot  - 38 results

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...pharmacologically-active ergot alkaloids, each...properties. All of these ergots stimulate the brains...repercussion of ergots vasoconstrictive...abdominal pain (31). Ergot compounds are also...everything was ergotism. Ergot toxicity tends to...diseases, and because ergots effects are enhanced...
...benefits may cause severe reaction or even death. Ergot derivatives have important uses in obstetrics;114 however, ergot can lead to major toxicity if used incorrectly: The dramatic effect of ergot ingested during pregnancy has been recognized...
...epidemics caused by the contamination of rye with ergot, a poisonous fungus. Ergot contains the potent toxin ergotamine, the consumption...notorious 1691-92 Salem witch trials also relates to ergot contamination. Three young girls suffered violent...
...and emmenagogues as quinine, aloes, or ergot; the third, douching by syringe or enema...trial a druggist described the policing of ergot and savin: "They both come under Schedule...herself several weeks late went to buy ergot pills, "Mrs. Sumners Remedies," and...
...rather claiming that bromocriptine was an ergot alkaloid, which had been shown to have...different chemical structure than other ergot alkaloids known to cause vasoconstriction...assumption that bromocriptine behaves like other ergot alkaloids carries little scientific value...
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magazine articles on: Ergot  - 50 results

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...Carl A. P. Ruck collaborate here to propose that ergot was the secret of the kykeon drunk at the Eleusinian...give this book the hearing it deserves. "We analyzed ergot of wheat and ergot of barley in our laboratory and they were found to...
...Some conditions contraindicate the use of ergot compounds because of the potential for...offers a departure from treatment with ergot products alone, for which there is a potential...anatomical site of the therapeutic action of ergot alkaloids in migraine remains uncertain...
...a mild attack, if given early enough. Ergot alkaloids may be prescribed for acute attacks...painkilling or sedative effects, however. Ergot is available as a single ingredient in...and relax the patient. Brand names of ergot preparations include Cafergot, Cafergot...
...receptor agonists are utilized, such as ergot alkaloids (bromocriptine and pergolide...L-DOPA usually do not respond well to ergot alkaloid dopamine receptor agonists, either. Both bromocriptine and pergolide are ergot alkaloids. Pergolide is less selective...
...class of medications can be divided into two categories: ergot derivatives (bromocriptine and pergolide) and non-ergot derivatives (pramipexole, ropinirole, and rotigotine).The ergot derivatives have fallen out of favor, mainly because...
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newspaper articles on: Ergot  - 12 results

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...a report on the North Coast of high levels of ergot infestation in sorghum. Sorghum ergot is caused by a fungus, Claviceps africana. The...nutritional value and due to the presence of the ergot fungal bodies called sclerotes. Infection is...
...hippy movement of the Sixties. Known as ergot poisoning or Saint Anthonys fire, the...hallucinations, were said to have resulted from ergot poisoning from damp rye flour. Less than...years as being the most striking example of ergot poisoning in modern times. Case closed...
...epidemicpestilence, the other invoked whenever St Antonys Fire (ergot) swept throughthe populace after eating mouldy ryefire because...reference less to syphilis (the usual explanation) than to the ergot thatmust have been the hospitallers main preoccupation. And...
...triggered dancing mania. Some blame it on unwitting consumption of ergot, a fungus that contains LSD. But it had also been noted that...dont for a moment suggest that Bill Whelan was tossing down the ergot in generous lumps, but he did write a piece of music that unleashed...
...report on the North Coast of high levels of fungus-induced "ergot infestation" in sorghum. It has warned the fungus diseases...forage sorghum crops they should be watched closely for signs of ergot poisoning". "Signs may indicate overheating such as excessive...
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encyclopedia articles on: Ergot  - 11 results

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ERGOT ur g t, disease of rye and other cereals...pink or purple body, the sclerotium, or ergot, that resembles a grain of rye in shape...that are toxic to humans and livestock. Ergot poisoning, or ergotism, epidemic in the...
...opposing physiological effects, stimulation of one system amounts to depression of the other. Some of the alkaloids from the ergot fungus act by direct stimulation of smooth muscle, inducing contractions in uterine and intestinal muscle...
...Some mushrooms contain substances that produce hallucinatory states, e.g., Psilocybe mexicana (see hallucinogenic drug ; ergot ). Occasional outbreaks of poisoning from eating canned mushrooms are not caused by poisonous mushrooms but by botulism resulting...
...have fed on poisonous plankton also are a cause of food poisoning, since the poisonous substance is not destroyed by cooking. Ergot poisoning, caused by ingestion of rye grain infected with that fungus, causes damage to the blood vessels and gangrene, as...
...which cause diseases of plants . Some molds produce toxic chemicals called mycotoxins that can cause serious diseases (see ergot ). Some organisms traditionally thought to be mold (e.g., slime molds ) have now been placed in the kingdom Protista...
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