GLOBULIN

any of a large family of proteins of a spherical or globular shape that are widely distributed throughout the plant and animal kingdoms. Many of them have been prepared in pure crystalline form. The term globulin is a partly procedural one, used in classifying an otherwise diverse group of proteins that are soluble in water or dilute salt solutions. Among the most important are the immunoglobulins (Ig), the antibodies of the immune system (see immunity). They are classified into five types based upon structure: IgA, IgD, IgE, IgG, and IgM. IgG or γ-globulin is the most common and forms about 70% of the immunoglobins in the blood. Other globulins are involved in the transport of a variety of substances, including lipids, hormones, and inorganic ions.

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The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

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Questia Books and Articles on: Globulin
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books on: Globulin  - 297 results

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...which has little or no detectable -globulin before ingestion of colostrum, and the newborn rabbit, with only 0.2 per cent globulin Haurowitz, 1950, p. 155 . However...serum contains substances, probably globulins, which flocculate saline tissue extracts...
...alpha, apoptosis, tumor necrosis factor, immuno- globulins, and heavy chains. However, here are some basics...in the recipients body. Immune human serum globulin (IHSG, gamma globulin ) is the most frequently used antibody preparation...
...the separate or globular molecules of globulin and albumin. Each molecule is probably...fishes it is almost entirely protamine. Globulin may be present as well, but the evidence...precipitate when added to a solution of globulin or albumin, while the latter do not...
...Localization of Two Genetic Factors to Different Areas of -Globulin Molecules by M. Harboe, C. K. Osterland, and H. G. Kunkel...Structural Basis for Genetic Variations of Normal Human - Globulins by Edward C. Franklin, Hugh Fudenberg, Martin Meltzer...
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journal articles on: Globulin  - 112 results

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...blood urea nitrogen, down arrow albumin:globulin ratio), carbohydrate (down arrow glucose...measured sodium, potassium, and chloride. Globulin concentrations were determined by subtracting...summationDDTs. The ratio of albumin to globulin was negatively correlated with concentrations...
...sexual partner were provided with immune globulin to prevent illness. In addition, the...advise restaurant patrons to get an immune globulin (IG) shot at the clinic to prevent potential...900 hours), related benefits, immune globulin, administrative support, and supplies...
...most well-documented example of alpha2u-globulin-associated renal carcinogenesis in the...plasma for all assays. Kidney. alpha2u-Globulin distribution was determined by immunohistochemistry...from these groups confirmed that alpha2u-globulin was increased with DCB and LIM but not...
...consumption with sex hormone-binding globulin (SHBG)-bound testosterone, but no association...to fill the unbound thyroxine-binding globulin (TBG) sites. The remaining tracer was...Northwestern University. Sex hormone-binding globulin. We used the Delphia system for the assay...
...three binding proteins, thyroxine-binding globulin, albumin, and transthyretin. The chemical...species. In humans, thyroxine-binding globulin is the major binding protein; in rodents...proteins, that is, thyroxine-binding globulin, in the adult rat plays a role, leading...
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magazine articles on: Globulin  - 45 results

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CMV Immune Globulin for Transplant Patients. A new immune globulin has been licensed to help protect transplant patients...carried by donated kidneys. Cytomegalovirus Immune Globulin Intravenous (Human), or CMV-IGIV, licensed by FDA...
...have been completed. U.S. Bioscience Inc., of West Conshohocken, Pa., manufactures NeuTrexin. New Uses for IGIV Immune Globulin Intravenous (Human) (IGIV), first licensed by FDA in 1981 to treat immune deficiency syndromes, was licensed Dec. 27, 1993...
...previously licensed biologic, intravenous immune globulin--Immune Globulin Intravenous (Human)to help minimize the complications...a combination of aspirin and intravenous immune globulin (often abbreviated IGIV) is highly effective in...
...WinRho SD, the product - Rho(D) Immune Globulin Intravenous (Human), or RhiGIV - is the...inactivation step as an added safeguard. Immune globulin lots are already tested for hepatitis...other nonspecific intravenous immune globulins to treat ITP in Rh positive patients...
...treatment was repeated transfusions of gamma globulin, which still left her exposed to a host...happening with Cytomegalovirus Immune Globulin Intravenous, or CMV-IGIV, a biologic...purposes, and biologics such as immune globulin for rare disorders. President Reagan...
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newspaper articles on: Globulin  - 18 results

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...vaccinations - hepatitis A or immune globulin (IG); hepatitis B for those who may be...vaccinations - hepatitis A or immune globulin (IG); hepatitis B (see conditions for...vaccinations - hepatitis A or immune globulin (IG), except travelers to Japan; hepatitis...
...dysfunction and mental health consequences. Sex hormone binding globulin (SHBG) is the protein that binds the hormone testosterone...consequence of the chronic elevation in sex hormone binding globulin levels, pill users may be at risk for long-standing health...
...acne and glycemic control. These included sex hormone binding globulin, androgen steroids, insulinlike growth factor-I, and insulinlike...proteins. In male teenagers, increased sex hormone binding globulin and androgenlike steroids are correlated with increased incidence...
...one of the highest rates of tummy bugs in the world." He recommends: IF YOU are leaving the UK in 24 hours, have a gamma globulin injection for hepatitis A. It protects you for two months. BOOST your tetanus and polio vaccinations - they take five days...
...chuckles Kingsley. Apparently, alcohol increases the production of sex-hormone binding globulin, or SHGB. If all your sex-hormones are bound to bits of globulin, they cant go off and attack your follicles. On the other hand, youll have a permanent...
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encyclopedia articles on: Globulin  - 12 results

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GAMMA GLOBULIN a group of globulin proteins in human blood plasma, including most antibodies...disease-producing organisms (see immunity ). Injections of gamma globulin are used to create a rapid but temporary immunity in patients...
GLOBULIN any of a large family of proteins of a spherical...have been prepared in pure crystalline form. The term globulin is a partly procedural one, used in classifying an otherwise...upon structure: IgA, IgD, IgE, IgG, and IgM. IgG or -globulin is the most common and forms about 70% of the immunoglobins...
...arthritis , a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individuals own gamma globulin blood proteins; the circulating complex apparently causes tissue inflammation and muscle and bone deformities. In Hashimotos...
...stored in the follicle stems between thyroid cells. Thyroxine enters into the bloodstream complexed to another protein, plasma globulin. Thyroxine increases the number and activity of mitochondria in cells by binding to the cells DNA, increasing the basal metabolic...
...kidney stimulates certain kidney cells to secrete the proteolytic enzyme renin, which converts the inactive angiotensinogen globulin in the blood into angiotensin I. Another enzyme then converts angiotensin I into angiotensin II, its active form. This peptide...
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