MEPROBAMATE

məprōˈbəmātˌ, tranquilizing drug that acts as a depressant of the central nervous system and is commonly used in the treatment of anxiety and sometimes schizophrenia. Although meprobamate is chemically unlike barbiturates and has lower toxicity, it has similar pharmacological effects, especially the ability to induce sleep and alleviate anxiety. The drug possesses some anticonvulsant properties and is used to suppress some forms of epilepsy. A muscle relaxant, meprobamate is also used to treat abnormal motor activity. It is marketed under the trade names Equanil and Miltown.

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The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

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Questia Books and Articles on: Meprobamate
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books on: Meprobamate  - 123 results

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...to the question of instinctual energy, is exemplified by that of Hess 1957 who examined the effects of chlorpromazine, meprobamate, and pentobarbital on imprinting in birds. Tranquilizing drugs have been found to retard the learning of conditioned responses...
...the derivative that became known as meprobamate. Were it not for the discovery...medicine encouraged Berger to find out if meprobamate could also be used for some form of...excited him was his observation that meprobamate seemed to be better than phenobarbital...
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journal articles on: Meprobamate  - 12 results

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...noteworthy. Carpenter was also lead investigator on the alcohol-meprobamate studies conducted at the Addiction Research Foundation, in...reported in Drug Interactions: The Effects of Alcohol and Meprobamate Applied Singly and Jointly in Human Subjects (1975). The...
...striking increase in the rate of blood clearance of ethanol, meprobamate (Salaspuro and Lieber, 1978), pentobarbital (Misra et al...ISHII, H., RUBIN, E. AND LIEBER, C.S. Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration...
...associated with the disease, which affects the nervous system, Dr. Hammargren prescribed quaaludes, valium, elavil, triavil, meprobamate, chloral hydrate, phenobarbitol, seconal, and talwin to combat her anxiety. (188) These drags are depressants with the "recognized...
...between two different drug regimes.) Widely-prescribed tranquilizers began to give doctors new weapons and new appeal; Miltown (Meprobamate) was the first "minor" tranquilizer available for anxiety. Antidepressant drugs soon followed. With housewives the principal...
...in addictive withdrawal has also decreased because they can be deadly when combined with alcohol or other CNS depressants. Meprobamate (EqanilTM and MiltownTM) is very similar to the barbiturates in most respects. Finally, beta-adrenergic blockers such as...
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magazine articles on: Meprobamate  - 2 results

 
 
...medication. Then the doctor may prescribe a minor tranquilizer. At one time drugs such as the barbiturates (phenobarbital) and meprobamate (Miltown and Equanil) were used to treat anxiety. However, because their use may lead to dependency and withdrawal seizures...
...wastewater--an antibiotic, a chemical used in perfume production, the muscle relaxant drug carisoprodol, and its metabolite meprobamate, among others. Meanwhile, in metropolitan Kansas City, more than 40 percent of stream samples analyzed by U.S. Geological...


 

newspaper articles on: Meprobamate  - 1 result

 
 
...swollen considerably, from 1,400 to 1,575 grams. Chow later claimed that Lee was allergic to Equagesic, an analgesic containing meprobamate, aspirin and ethoheptazine. Eventually, a verdict of death by misadventure was pronounced, listing the cause of death as...


 

encyclopedia articles on: Meprobamate  - 7 results

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MEPROBAMATE m pro b mat , tranquilizing drug that acts as a...anxiety and sometimes schizophrenia . Although meprobamate is chemically unlike barbiturates and has lower toxicity...suppress some forms of epilepsy . A muscle relaxant, meprobamate is also used to treat abnormal motor activity. It is...
MILTOWN see meprobamate . ____________________ Copyright 2009 Columbia University Press. Used with the permission of Columbia University Press. All rights reserved.
...early 1960s with chlordiazepoxide (Librium), benzodiazepines were heralded as a safer alternative to barbiturates and meprobamate because they were relatively non habit forming and were less lethal in overdose. There has been considerable debate over...
...diminish functional activity, usually by depressing the nervous system . Barbiturates , sedatives , alcohol, and meprobamate are all depressants. Depressants have various modes of action and effects. Some are primarily used medically to relieve...
...hypnotics (see hypnotic drugs ), i.e., they induce sleep, and as anesthetics. Many sedatives, including barbiturates , meprobamate (Miltown), and benzodiazepines (Librium and Valium), are habit-forming and should be taken only under medical direction...
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