Should Two Research Institutes Become ONE?

Article excerpt

Fears over a possible NIDA-NIAAA merger focus on the alcohol community

When Congress adopted the NIH (Nacional Institutes of Health) Reform Act of 2006, it created a Scientific Management Review Board (SMRB) charged with making recommendations about establishing or abolishing institutes under NIH. Two institutes of great importance to the addiction treatment community - the National Institute on Alcohol Abuse" and Alcoholism (NIAAA) and the Rational Institute on Dr-ug Abuse (NIDA) - are presently under close scrutiny.

During four meetings held last year, and another meeting with the NIAAA council that took place Feb. 3, the Substance Use, Abuse, and Addiction Working Group of the SMRB heard presentations from stakeholders on a possible merger of NIDA and NIAAA. The working group was to present a full range of options to die SMRB on March 10, and in May there will be a recommendation for a final decision, which ultimately will be made by NIH director Francis S. Collins, MD, PhD.

Not far beneath that landscape of facts lies a wellspring of emotion and fear. Alcohol researchers and the NIAAA community are deeply worried riiat in any merger, NLAAA would be the loser and NIDA would be the winner. As one observer put it: "To NIAAA, it's a merger. To NIDA, it's an acquisition."

Not only are alcohol researchers worried about losing money, but they also are troubled by the possible loss of alcohol's unique identity as the primary drug of abuse, and a pervasive sense that the value of their work is not being recognized. Basically, those in favor of the merger ask, "Why not?" and say "The science is the same," and those opposed ask, with anguish, "Why?" and say "The science is not the same!"

The discussion has led to divisiveness, putting long-time colleagues and friends on opposite sides of the issue. And while current employees of NIDA and NLAAA will not discuss this sensitive topic publicly, former ones do - none more eloquently than Enoch Gordis, MD.

"This is clearly not a time to bury die NLAAA," wrote Gordis, former NLAAA director for 15 years, in written closed testimony to the Substance Use, Abuse, and Addiction Working Group last December. "That would be a terrible message to the American public and to the global community," he wrote, adding that the World Health Organization has found that alcohol is the fifth leading cause of premature death and disability worldwide. "I ask this committee and the NIH: please don't take the sign off the door."

Alcohol is unique in its actions and in the scale of the problems it causes, wrote Gordis. "The statement regarding both institutes that 'the science is the same,' which comes so trippingly off the tongue, is a serious misrepresentation of the scientific reality, and results from a very narrow perspective of the universe in which alcohol issues, problems and science play out."

Most alcohol abusers and alcoholics are not drug abusers, Gordis points out - of the 18 million adults with an alcohol use disorder, only 13 percent also have a drug abuse disorder.

Recovering alcoholics

Another key participant in the discussion is the recovering community, which traditionally has had a close connection with NIAAA. The late U.S. Sen. Harold E. Hughes, a recovering alcoholic, helped created the Comprehensive Alcohol Abuse and Alcoholism Prevention, Treatment and Rehabilitation Act of 1970, legislation that established NlAAA. Hughes believed that alcohol research needed its own "highly visible agency," recalled Cordis. And Bill Wilson, the founder of Alcoholics Anonymous (AA), broke his anonymity to testify before Congress on behalf of establishing NLAAA.

Invoking the name of Bill Wilson is a sign of some of the unspoken differences between NIDA and NLAAA - many people who want NIAAA to remain a separate institute are recovering alcoholics, with all of the personal investment that entails.

Gordis's letter, along with one from Ting-Kai Li, MD, NLAAA director from 2002 to 2008, was made public by the Research Society on Alcoholism on Jan. …