kärĕlˈ, kə–, 1873–1944, American surgeon and experimental biologist, b. near Lyons, France, M.D. Univ. of Lyons, 1900. Coming to the United States in 1905, he joined the staff of the Rockefeller Institute in 1906 and served as a member from 1912 to 1939. For his work in suturing blood vessels, in transfusion, and in transplantation of organs, he received the 1912 Nobel Prize in Physiology or Medicine. In World War I he developed, with Henry D. Dakin, a method of treating wounds by irrigation with a sodium-hypochlorite solution. With Charles A. Lindbergh he invented an artificial, or mechanical, heart, by means of which he kept alive a number of different kinds of tissue and organs; he kept tissue from a chicken's heart alive for 32 years. In 1939 he returned to France. He wrote Man the Unknown (1935) and, with Lindbergh, The Culture of Organs (1938).

The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

-8711-