in psychiatry, treatment of mood disorders by means of electricity; the broader term "shock therapy" also includes the use of chemical agents. The therapeutic possibilities of these treatments were discovered in the 1930s by Manfred Sakel, a Polish psychiatrist, using insulin; L. J. Meduna, an American psychiatrist, using Metrazol; and Ugo Cerletti and Lucio Bini, Italian psychiatrists, using electric shock. Metrazol and insulin accounted for a very limited number of remissions in cases of schizophrenia. However, the injection of insulin often caused coma, while Metrazol and electric shock resulted in convulsions similar to those of epileptics. Advances in electroconvulsive therapy (ECT) have made it the standard mechanism of shock therapy. ECT has had unquestionable success with involutional melancholia and other depressive disorders, yet many specialists still consider it an unneccessarily dangerous method. It is still in common use at most major medical centers, although it is generally employed only after other therapies have proven ineffective.

See A. S. Hermreck and A. P. Thal, The Adrenergic Drugs and Their Use in Shock Therapy (1968); L. B. Kalinowsky and H. Hippius, Pharmacological, Convulsive, and other Somatic Treatments in Psychiatry (1969).

The Columbia Encyclopedia, Sixth Edition Copyright© 2004, Columbia University Press. Licensed from Lernout & Hauspie Speech Products N.V. All rights reserved.

-15214-