săgˈĭnô, city (1990 pop. 69,512), seat of Saginaw co., S Mich., on the Saginaw River, 15 mi (24 km) from its mouth on Saginaw Bay (an inlet of Lake Huron); settled 1816, inc. 1857. Situated in an extensive agricultural area, Saginaw is also a port of entry with diversified industries. Nearby are major salt, coal, and oil deposits. Native American trails once crossed the city's site, and local native villages were abundant. Lewis Cass negotiated a treaty there (1819) with the indigenous groups, who ceded much of Michigan to the United States. Fur trade was followed by a great pine-lumbering industry, which thrived until about 1890. The old Schuch Hotel (1868) has an interesting collection of antiques.

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