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A Means to an End: The Biological Basis of Aging and Death

By: William R. Clark | Book details

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Contents
Acknowledgments,ix
Introduction,xiii
1 Aging, Senescence, and Lifespan,3
2 The Nature of Cellular Senescence and Death,21
3 The Evolution of Senescence and Death,41
4 Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan,59
5 Human Genetic Diseases That Mimic the Aging Process,73
6 Cycling to Senescence,95
7 Replicative Immortality: Cancer and Aging,115
8 Caloric Restriction and Maximum Lifespan,131
9 With Every Breath We Take: Oxidative Stress and Cellular Senescence,149
10 The Aging Brain,169
11 A Conditional Benefit,189
Bibliography,221
Index,229

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