The genetics of type 2 diabetes, MODY, and other syndromesWilliam E Winter
IntroductionThe forms of non-insulin-dependent-non-autoimmune diabetes affecting children include:
|2. maturity-onset diabetes of the young (MODY)|
|3. mitochondrial diabetes and|
|4. other specific types of diabetes such as diabetes secondary to cystic fibrosis.|
The genetics of each condition is discussed below.
Type 2 diabetes: genetic overview
There is convincing evidence that genetics plays a major role in the etiology of type 2 diabetes in adults.
1 Among people with type 2 diabetes, there is often a very strong family history of similarly affected individuals: familial aggregations of type 2 diabetes are common. Because lifestyle patterns that lead to obesity are so ingrained into everyday life and family habits, it is often difficult to separate nature versus nurture.
Questia, a part of Gale, Cengage Learning. www.questia.com
Book title: Type 2 Diabetes in Childhood and Adolescence: A Global Perspective.
Contributors: Martin Silink - Editor, Kaichi Kida - Editor, Arlan L Rosenbloom - Editor.
Publisher: Martin Dunitz.
Place of publication: London.
Publication year: 2003.
Page number: 211.
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