The Management of Obesity and Related Disorders

By Peter G. Kopelman | Go to book overview
Save to active project

10

Pharmacological approaches

John Wilding

Introduction

Drug treatment of obesity has had a chequered, and at times controversial history, and it is important to consider the currently available treatments in the light of this previous experience. Many of the older agents were never rigorously evaluated in the way that would be considered the minimum standard today, and the evidence of their effectiveness was often based on small, short-term studies, with little attempt to investigate effects on the co-morbidities of obesity. Some of these agents also turned out to have serious adverse effects, which has resulted in their withdrawal for safety reasons. Two new drugs (orlistat and sibutramine) have recently been approved for use in many countries and, at present, seem to be at least as effective, and safer, than the older drugs; furthermore, there are many more data about their effectiveness in terms of the co-morbidities of obesity. Nevertheless, as clinicians it is important to ensure that such drugs are used in an appropriate and responsible manner, using the best available evidence. This chapter will briefly describe the range of possible options in the pharmacotherapy of obesity, discuss when it might be appropriate to consider

-203-

Notes for this page

Add a new note
If you are trying to select text to create highlights or citations, remember that you must now click or tap on the first word, and then click or tap on the last word.
Loading One moment ...
Project items
Notes
Cite this page

Cited page

Style
Citations are available only to our active members.
Sign up now to cite pages or passages in MLA, APA and Chicago citation styles.

Cited page

Bookmark this page
The Management of Obesity and Related Disorders
Settings

Settings

Typeface
Text size Smaller Larger
Search within

Search within this book

Look up

Look up a word

  • Dictionary
  • Thesaurus
Please submit a word or phrase above.
Print this page

Print this page

Why can't I print more than one page at a time?

While we understand printed pages are helpful to our users, this limitation is necessary to help protect our publishers' copyrighted material and prevent its unlawful distribution. We are sorry for any inconvenience.
Full screen
/ 258

matching results for page

Cited passage

Style
Citations are available only to our active members.
Sign up now to cite pages or passages in MLA, APA and Chicago citation styles.

Cited passage

Welcome to the new Questia Reader

The Questia Reader has been updated to provide you with an even better online reading experience.  It is now 100% Responsive, which means you can read our books and articles on any sized device you wish.  All of your favorite tools like notes, highlights, and citations are still here, but the way you select text has been updated to be easier to use, especially on touchscreen devices.  Here's how:

1. Click or tap the first word you want to select.
2. Click or tap the last word you want to select.

OK, got it!

Thanks for trying Questia!

Please continue trying out our research tools, but please note, full functionality is available only to our active members.

Your work will be lost once you leave this Web page.

For full access in an ad-free environment, sign up now for a FREE, 1-day trial.

Already a member? Log in now.

Are you sure you want to delete this highlight?