Prusiner, Stanley Ben
Stanley Ben Prusiner, 1942–, American neurologist, b. Des Moines, Iowa, M.D. Univ. of Pennsylvania School of Medicine, 1968. Prusiner has been a professor at the Univ. of California, San Francisco since 1974. In 1997 he received the Nobel Prize in physiology or medicine for his discovery of prions, a new type of infectious agent. Normally existing as innocuous cellular proteins, prions can cause deadly brain diseases when genetic mutations occur. His work determined the cause of bovine spongiform encephalopathy ( "mad cow disease" ) and a similar disorder in humans, Creutzfeldt-Jakob disease; his findings also laid the foundation for uncovering the cause of other diseases that cause dementia, such as Alzheimer's disease.
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Publication information: Article title: Prusiner, Stanley Ben. Encyclopedia title: The Columbia Encyclopedia, 6th ed.. © 2012 The Columbia Electronic Encyclopedia © 2012, Columbia University Press. Licensed from Columbia University Press. Used with the permission of Columbia University Press. All Rights Reserved. Publisher: The Columbia University Press. Place of publication: Not available. Publication year: 2013.
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