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Heart Disease, Diabetes Risk Appear Absent with Ziprasidone

By: Walsh, Nancy | Clinical Psychiatry News, December 2006 | Article details

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Heart Disease, Diabetes Risk Appear Absent with Ziprasidone


Walsh, Nancy, Clinical Psychiatry News


NEW YORK -- Unlike other atypical antipsychotics, ziprasidone was not found to increase the risk for diabetes or cardiovascular disease in an analysis of data from the Clinical Antipsychotic Trials in Intervention Effectiveness study.

Results from CATIE indicated that patients with schizophrenia at baseline are at increased risk of coronary heart disease (CHD), compared with age- and sex-matched controls, according to Brian J. Cuffel, Ph.D., of Pfizer Inc.

CATIE included 1,493 patients with schizophrenia recruited from 57 clinical facilities in the United States. At baseline, fasting laboratory values were obtained and patients randomly assigned to treatment with …

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