Treatment of Migraine: An Armory of Therapeutic Drugs from Which to Choose
Mild Episodes of Migraine
Simple analgesics, like aspirin or acetaminophen, may be all that is required for mild episodes of migraine.
For more intense cases of migraine, various nonsteroidal anti-inflammatory drugs (NSAIDs) are usually prescribed:
Indomethacin -- Not recommended for patients with liver disease, ulcers, or other stomach problems. Inform your doctor if you are taking medications to prevent blood clots. Report bloody stools or blurred vision.
Ibuprofen (Motrin, Advil, Nuprin) -- Side effects can include diarrhea, dizziness, constipation, dry mouth, fluid retention, stomach ulcers, damage to the cornea, kidney damage, and reduced white blood cell count. Report other medication use.
Naproxen -- Has risen to prominence in the treatment of migraine because of reported tolerance and record of safety.
Moderate to Severe Episodes of Migraine
Ergotamine -- Ergotamine tartrate has been in use since 1928 (similar formulas are Cafergot, Ergomar, Ergostat Gynergen). Rectal suppositories of ergotamine are available and are more rapidly absorbed. Excessive use of ergotamine can result in cold, clammy extremities (vasoconstriction), chest pain, claudication of legs, and numbness of hands and feet. Inform your doctor immediately of severe abdominal pain. Do not take if you are hypertensive or have a peptic ulcer, kidney disease, or a liver disorder.
Sumatriptan (Imitrex) -- Heralded as the innovation of the decade, sumatriptan is considered a major advance in migraine therapy. Injection preparations are available in the United States. Oral preparations can be procured in some other countries (Canada). Glaxo, the maker of Imitrex, promises availability in the United States by …
Questia, a part of Gale, Cengage Learning. www.questia.com
Publication information: Article title: Treatment of Migraine: An Armory of Therapeutic Drugs from Which to Choose. Contributors: Not available. Magazine title: Nutrition Health Review. Issue: 70 Publication date: Summer 1994. Page number: 3. © 1996 Vegetus Publications. COPYRIGHT 1994 Gale Group.
This material is protected by copyright and, with the exception of fair use, may not be further copied, distributed or transmitted in any form or by any means.