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Heart Rate Changes after Stimulants Negligible

By: McNamara, Damian | Clinical Psychiatry News, December 2010 | Article details

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Heart Rate Changes after Stimulants Negligible


McNamara, Damian, Clinical Psychiatry News


BOCA RATON, FLA. -- The use of methylphenidate or mixed amphetamine salts for attention-deficit/hyperactivity disorder can increase heart rate, blood pressure, and the QT interval in children, adolescents, and adults, according to a review of placebo-controlled and open-label extension trials published since 2000.

The magnitude of the effects appears small for most patients, which points to the importance of screening for preexisting cardiovascular disease and asking about any relevant family or patient history, Dr. Raul R. Silva said.

Despite long-term use and the effectiveness of these stimulant medications to reduce core symptoms of ADHD, concerns arose about increased potential for cardiovascular events. The American Heart Association released guidelines for cardiac monitoring of all children with ADHD before …

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