Gene Mutations Affect Cognition, Emotions. (Imaging Studies)
Evans, Jeff, Clinical Psychiatry News
BETHESDA, MD. -- Specific mutations to single genes may help predispose some patients to abnormal behaviors, Dr. Daniel R. Weinberger said at a psychopharmacology update sponsored by the National Institute of Mental Health.
In imaging studies, seemingly insignificant polymorphisms in three well-studied genes have been observed to have a relatively large impact on information processing and emotional responses.
Several studies have focused on the effects of a single-base pair substitution in the gene that codes for catechol-O-methyl-transferase (COMT), which breaks down dopamine, said Dr. Weinberger, chief of the clinical brain disorders branch of the National Institute of Mental Health.
The mutation makes the COMT enzyme about …
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Publication information: Article title: Gene Mutations Affect Cognition, Emotions. (Imaging Studies). Contributors: Evans, Jeff - Author. Magazine title: Clinical Psychiatry News. Volume: 31. Issue: 2 Publication date: February 2003. Page number: 34+. © 2009 International Medical News Group. COPYRIGHT 2003 Gale Group.
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