Watchdog Warns of Prozac Suicide Risk
Jeremy Laurance and David Usborne, The Independent (London, England)
THE GOVERNMENT came under pressure yesterday to ban the use of the antidepressant drug Prozac in children after US regulators warned that it could increase the risk of suicide.
Prozac is the only antidepressant that doctors can prescribe to children in Britain following a safety review last year. The drug was singled out by the UK Medicines and Healthcare Products Regulatory Authority (MHRA) as the only one of the modern generation of antidepressants that was effective and safe in children. All others were banned for children last December.
But US regulators claim there is nothing to distinguish the drugs, known as selective serotonin uptake inhibitors (SSRIs) and all are risky in children. "I think we now all believe that there is an increase in suicidal thinking and action that is consistent across all the drugs," Robert Temple, the director of the FDA's office of medical policy, said on Monday.
He was speaking at the first day of hearings in Washington on whether antidepressants should have tougher warning labels. An advisory committee of the Food and Drug Administration (FDA) was expected to announce the new curbs last night after two days of hearings.
The curbs are likely to involve more explicit labelling to discourage their distribution to young people or an outright ban.
Disclosure of the US authorities' view that there were problems with Prozac alarmed psychiatrists in Britain. Tim Kendall, head of research at the Royal College of Psychiatrists, who published a survey of research on antidepressants in children earlier this year, said: "We got all the published trials and the unpublished material from the MHRA and we couldn't find that. If the FDA has come up with something [in …
Questia, a part of Gale, Cengage Learning. www.questia.com
Publication information: Article title: Watchdog Warns of Prozac Suicide Risk. Contributors: Jeremy Laurance and David Usborne - Author. Newspaper title: The Independent (London, England). Publication date: September 15, 2004. Page number: 4. © 2009 The Independent - London. Provided by ProQuest LLC. All Rights Reserved.
This material is protected by copyright and, with the exception of fair use, may not be further copied, distributed or transmitted in any form or by any means.