Genetic Research: Who Is at Risk for Alcoholism?

Foroud, Tatiana, Edenberg, Howard J., Crabbe, John C., Alcohol Research & Health

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) was founded 40 years ago to help elucidate the biological underpinnings of alcohol dependence, including the potential contribution of genetic factors. Twin, adoption, and family studies conclusively demonstrated that genetic factors account for 50 to 60 percent of the variance in risk for developing alcoholism. Case-control studies and linkage analyses have helped identify DNA variants that contribute to increased risk, and the NIAAA-sponsored Collaborative Studies on Genetics of Alcoholism (COGA) has the expressed goal of identifying contributing genes using state-of-the-art genetic technologies. These efforts have …

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Publication information: Article title: Genetic Research: Who Is at Risk for Alcoholism?. Contributors: Foroud, Tatiana - Author, Edenberg, Howard J. - Author, Crabbe, John C. - Author. Journal title: Alcohol Research & Health. Volume: 33. Issue: 1/2 Publication date: January 1, 2010. Page number: 64+. © 2008 U.S. Government Printing Office. Provided by ProQuest LLC. All Rights Reserved.

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