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Girth Control

By: Rodgers, Katie | Drug Topics, May 2, 1996 | Article details

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Girth Control


Rodgers, Katie, Drug Topics


First weight loss Rx in 20 years clears the FDA

Redux (dexfenfluramine, Interneuron Pharmaceuticals), a serotonergic appetite suppressant, has received Food & Drug Administration approval for the management of obesity in patients on a reduced-calorie diet. It is approved for both initial weight loss and maintenance of weight loss, so pharmacists can expect to see it used long-term. The first appetite suppressant to clear the FDA in 20 years, dexfenfluramine has been available in Europe for more than a decade and has been used by an estimated 10 million patients.

Dexfenfluramine appears to increase serotonin levels by three different mechanisms. Robert Kushner, M.D., …

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