erating axons. Furthermore, it is crucial to define the factors that are responsible for the formation of correct and appropriate new synapses once the regenerating axons get back to the correct target cells.
As methods and procedures for identifying these factors become available through an acceleration in the understanding and application of molecular and cellular biology, it is becoming clear that in order to fully understand and test the efficacy of these molecules, valid and reliable in vivo models are crucial.
This understanding of the importance of integrative neurobiology and the value of neurobiologists who can bridge the skill sets of molecular, cellular, physiological, and behavioral neuroscience is the legacy that Bob Isaacson has left to his students and colleagues.
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Publication information: Book title: Neurobehavioral Plasticity:Learning, Development, and Response to Brain Insults. Contributors: Norman E. Spear - Editor, Linda P. Spear - Editor, Michael L. Woodruff - Editor. Publisher: Lawrence Erlbaum Associates. Place of publication: Hillsdale, NJ. Publication year: 1995. Page number: 215.
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