Encyclopedia of Reproductive Technologies

By Annette Burfoot | Go to book overview
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increase in incidence over the normal incidence for the population in question.
In summary, research has demonstrated that ovulation induction is associated with serious, sometimes life-threatening, events. Severe ovarian hyperstimulation syndrome still occurs in about 1 in 50 to 1 in 100 women in spite of careful monitoring. Multiple pregnancy frequently complicates ovulation-induced and assisted-conception pregnancies. Perinatal mortality is excessive. Recent data suggest that ovulation induction may also be a risk factor for extrauterine pregnancy, neural tube defects, defects in reproductive organogenesis, malignant neoplasms, and hydatidiform mole.
McEvoy, G. K., ed. 1990. American Hospital Formulary Services. Bethesda, Md.: American Society of Hospital Pharmacists.
Ron, E., B. Lunenfeld, J. Menczer, et al. 1987. "Cancer Incidence in a Cohort of Infertile Women." American Journal of Epidemiology 125( 5): 780-790.
Stephenson, P. 1993. "Ovulation Induction During Treatment for Infertility: An Assessment of the Risks." In P. Stephenson and M. G. Wagner, eds., "Tough Choices: In Vitro Fertilization and the Reproductive Technologies". Philadelphia: Temple University Press.
U.S. Pharmacopeial Convention. 1990. Drug Information for the Health Care Professional. Rockville, Md.: USPC.
Whittemore, A. S., et al. 1992. "Characteristics Relating to Ovarian Cancer Risk: Collaborative Analysis of 12 U.S. Case-control Studies." American Journal of Epidemiology 15: 1184-1203.


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Encyclopedia of Reproductive Technologies
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