root") obtained from West Africa.If this is ground to a powder and the powder set on fire, it produces a toxic smoke or fume that maddens and kills.

With more bravery than good sense, Holmes tests the substance on himself and on the ever-loyal Watson.Here is how Watson describes the effect:

I had hardly settled in my chair before I was conscious of a thick, musky odour, subtle and nauseous. At the very first whiff of it my brain and my imagination were beyond all control. A thick, black cloud swirled before my eyes, and my mind told me that in this cloud, unseen as yet, but about to spring out upon my appalled senses, lurked all that was vaguely horrible, all that was monstrous and inconceivably wicked in the universe. Vague shapes swirled and swam amid the dark cloud-bank, each a menace and a warning of something coming, the advent of some unspeakable dweller upon the threshold, whose very shadow would blast my soul. A freezing horror took possession of me. I felt that my hair was rising, that my eyes were protruding, that my mouth was opened, and my tongue like leather. The turmoil within my brain was such that something must surely snap. I tried to scream, and was vaguely aware of some hoarse croak which was my own voice, but distant and detached from myself."

A half-century later, the physiological effects of lysergic acid diethylamide (LSD) were discovered—though not in an African root—and the effects were not very different from those Watson described.It seems that Holmes and Watson had the equivalent of a "bad trip" decades before its time.

This is a remarkable bit of chemical science-fiction that came true, and it makes up to me for all the bits of poor chemistry Conan Doyle inserted into his stories.

-132-

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The Roving Mind
Table of contents

Table of contents

  • The Roving Mind *
  • Contents vii
  • Foreword Isaac Asimov: Science Popularizer, Skeptic, and Rationalist xi
  • A Celebration of Isaac Asimov — a Man for the Universe xv
  • Introduction 1
  • Part I the Religious Radicals *
  • 1: The Army of the Night *
  • 3: The Reagan Doctrine 20
  • 4: The Blind Who Would Lead 24
  • 5: Creeping Censorship 27
  • 6: Losing the Debate 29
  • Part II Other Aberrations 30
  • 7: The Harvest of Intelligence *
  • 8: That Old-Time Violence 37
  • 9: Little Green Men or Not? 40
  • 10: Don'T You Believe? 43
  • 11: Open Mind? 47
  • 12: The Role of the Heretic 49
  • Part III Population *
  • 13: The Good Earth is Dying *
  • 14: The Price of Survival 66
  • 15: Letter to a Newborn Child 72
  • Part IV Science: Opinion 74
  • 16: Technophobia *
  • 17: What Have You Done for Us Lately? 84
  • 18: Speculation 88
  • 19: Is It Wise for Us to Contact Advanced Civilizations? 92
  • 20: Pure and Impure 97
  • 21: Do We Regulate Science? 104
  • 22: For Public Understanding of Science 107
  • 23: Science Corps 110
  • 24: Science and Beauty 113
  • 25: Art and Science 116
  • 26: The Fascination of Science 120
  • 27: Sherlock Holmes as Chemist 127
  • Part V Science: Explanation 132
  • 28: The Global Jigsaw *
  • 29: The Inconstant Sun 139
  • 30: The Sky of the Satellites 151
  • 31: The Surprises of Pluto 157
  • 32: Neutron Stars 160
  • 33: Black Holes 162
  • 34: Faster Than Light 165
  • 35: Hyperspace 169
  • 36: Beyond the Universe 175
  • 37: Life on Earth 183
  • Part VI the Future 188
  • 38: Transportation and the Future *
  • 39: The Corporation of the Future 200
  • 40: The Future of Collecting 208
  • 41: The Computerized World 214
  • 42: The Individualism to Come 228
  • 43: The Coming Age of Age 237
  • 44: The Decade of Decision 244
  • 45: Do You Want to Be Cloned? 251
  • 46: The Hotel of the Future 256
  • 47: The Future of Plants 262
  • 48: Bacterial Engineering 266
  • 49: Flying in Time to Come 272
  • 50: The Ultimate in Communication 278
  • 51: His Own Particular Drummer 285
  • 52: The Future of Exploration 295
  • 53: Homo Obsoletus? 300
  • 54: Volatiles for the Life on Luna 307
  • 55: Touring the Moon 312
  • 56: Life on a Space Settlement 317
  • 57: The Payoff in Space 324
  • Part VII Personal *
  • 58: I Am a Signpost *
  • 59: The Word-Processor and I 334
  • 60: A Question of Speed 337
  • 61: A Question of Spelling 340
  • 62: My Father 344
  • Acknowledgments 348
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