more, of forming several crystalline combinations which do not show any hemihedrism. It was the first exception which Pasteur had encountered in this law of correlation between hemihedrism and the rotary power. Now, ac- cording to the current ideas of the epoch, fermentation was a disintegration: it was the breaking up of a molecule by decay, the débris of which, still voluminous, formed new molecular edifices which were the products of the fermentation. Consequently, by virtue of the theory of Liebig, the edifice of amyl alcohol must form some part of the framework in the molecule of the sugar in order to resist dismemberment, and as it preserves the rotary power its optical action must be derived from that of sugar. This idea was repugnant to Pasteur. He had seen, for example, in malic and maleic acids, that the least injury to the structure of the molecule made its rotary power disappear. "Every time," he says, "that we try to follow the rotary power of a body into its deriva- tives we see it promptly disappear. The primitive molecular group must be preserved intact, as it were, in the derivative, in order that the latter may continue to be active, a result which my researches permit me to predict, since the optical property is entirely dependent on a dissymmetrical arrangement of the elementary atoms. But I find that the molecular group of amyl alcohol is too far away from that of sugar, if derived from it, for it to retain therefrom a dissymmetrical arrange- ment of its atoms." The origin of this alcohol must, therefore, be more profound, and, recalling the before-mentioned fact that life alone is capable of creating full-fledged new dissym- metries, and thinking that his objection would no longer have a raison d'être, if between the sugar and the amyl alcohol a living organism were interposed, Pasteur -68- |