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No one can escape a sense of wonder when looking at an organism from within. From the humblest amoeba to man, from the smallest cell organelle to the amazing human brain, life presents us with example after example of highly ordered cellular matter, precisely organized and shaped to perform ...

No one can escape a sense of wonder when looking at an organism from within. From the humblest amoeba to man, from the smallest cell organelle to the amazing human brain, life presents us with example after example of highly ordered cellular matter, precisely organized and shaped to perform coordinated functions. But where does this order spring from? How does a living organism manage to do what nonliving things cannot do--bring forth and maintain all that order against the unrelenting, disordering pressures of the universe? In The Touchstone of Life, world-renowned biophysicist Werner Loewenstein seeks answers to these ancient riddles by applying information theory to recent discoveries in molecular biology. Taking us into a fascinating microscopic world, he lays bare an all-pervading communication network inside and between our cells--a web of extraordinary beauty, where molecular information flows in gracefully interlaced circles. Loewenstein then takes us on an exhilarating journey along that web and we meet its leading actors, the macromolecules, and see how they extract order out of the erratic quantum world; and through the powerful lens of information theory, we are let in on their trick, the most dazzling of magician's acts, whereby they steal form out of formlessness. The Touchstone of Life flashes with fresh insights into the mystery of life. Boldly straddling the line between biology and physics, the book offers a breathtaking view of that hidden world where molecular information turns the wheels of life. Loewenstein makes these complex scientific subjects lucid and fascinating, as he sheds light on the most fundamental aspects of our existence.

"This book is of special importance. Callahan brings together in one volume the history of biomedical research in the U.S., a discussion of the goals, process, and conduct of biomedical research, and a compelling proposal for reforming the balance between research and public health ...

"This book is of special importance. Callahan brings together in one volume the history of biomedical research in the U.S., a discussion of the goals, process, and conduct of biomedical research, and a compelling proposal for reforming the balance between research and public health policies."--Dorothy Rice, coauthor of The Dynamics of Disability: Measuring and Monitoring Disability for Social Security Programs

This is a comprehensive introduction to the ethical issues at stake in the conduct of biomedical research, with extensive use of case examples. Its content parallels the recommendations of the Commission on Research Integrity, and deals with ethical issues in the use of animal and humans in ...

This is a comprehensive introduction to the ethical issues at stake in the conduct of biomedical research, with extensive use of case examples. Its content parallels the recommendations of the Commission on Research Integrity, and deals with ethical issues in the use of animal and humans in research. It includes chapters on intellectual property, authorship, peer review, and conflicts of interest. As of October 2000, all personnel involved in research supported by the Public Health Service, including NIH, must receive the equivalent of 15 hours of training and education in research ethics. This book will be a convenient text for such short courses or seminars, and an excellent guidebook for all.