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Determinants of the Proinflammatory Action of Ambient Particulate Matter in Immortalized Murine Macrophages

Contributors:: Guastadisegni, Cecilia Kelly, Frank J. Cassee, Flemming R. Gerlofs-Nijland, Miriam E. Janssen, Nicole A. H. Pozzi, Roberta Brunekreef, Bert Sandstrom, Thomas Mudway, Ian
Publication:: Environmental Health Perspectives, Vol. 118, No. 12, December 2010
Subjects:: Particulate Matter--Health Aspects
Particulate Matter--Research
Air Pollution--Health Aspects
Air Pollution--Research
Macrophages--Research

Macrophages--Health Aspects Inflammation--Risk Factors Inflammation--Research Hydrocarbon Pollutants--Health Aspects Hydrocarbon Pollutants--Research
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...BACKGROUND: Proximity to traffic-related pollution has been associated with poor respiratory health in adults and children. OBJECTIVES: We wished to test the hypothesis that particulate matter (PM) from high-traffic sites would display an enhanced capacity to elicit inflammation. METHODS: We...

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