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Iwona J. Fijalkowska

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Dpb2p, a Noncatalytic Subunit of DNA Polymerase [Epsilon], Contributes to the Fidelity of DNA Replication in Saccharomyces Cerevisiae

Contributors:: Jaszczur, Malgorzata Flis, Krzysztof Rudzka, Justyna Kraszewska, Joanna Budd, Martin E. Polaczek, Piotr Campbell, Judith L. Jonczyk, Piotr Fijalkowska, Iwona J.
Publication:: Genetics, Vol. 178, No. 2, February 2008
Subjects:: E coli
Mutation
Kinases
Cancer
Genes

DNA Primers DNA-Binding Proteins Multienzyme Complexes Recombinant Proteins Saccharomyces cerevisiae Proteins DNA Polymerase II Dpb2 protein, S cerevisiae
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...ABSTRACT Most replicases are multi-subunit complexes. DNA polymerase epsilon from Saccharomyces cerevisiae is composed of four subunits: Pol2p, Dpb2p, Dpb3p, and Dpb4p. Pol2p and Dpb2p are essential. To investigate a possible role for the Dpb2p subunit in maintaining the fidelity of DNA...

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