International Journal of Collaborative Research on Internal Medicine & Public Health: Geographic and Ethnic Distribution of P Knowlesi Infection in Sabah, Malaysia

Article excerpt

Plasmodium knowlesi, an originally zoonotic malaria parasite is now increasingly recognized as a potentially virulent type of human malaria, particularly in Southeast Asia. The initial diagnosis based on light microscopy would not differentiate P knowlesi from P malaria and the nested PCR (Polymerase Chain Reaction) assay is the only reliable diagnostic method to correctly differentiate the two species. Sabah State Public Health Laboratory has launched its PCR service in 2007 for all government hospitals of Sabah to get accurate verification of malaria species. Sabah state is famous for its significant tourist attraction sites, of which Mount Kinabalu and Tip of Borneo are the most unique [sic] and mostly [sic] visited. A large variety of ethnic groups reside in Sabah with Kadazan-Dusun forming the largest indigenous group followed by Bajau and Murut.

Aim & Objectives: To determine the geographic and ethnic distribution of zoonotic malaria among Sabah population so as to recommend effective preventive and control measures at popular tourist sites of Sabah.

Methods/Study Design: A record review of all nested PCR assays done during 2009 at Sabah State Public Health Laboratory was made. SPSS version 16 and Microsoft excel 2007 softwares were used in analysis. …