Hypertension in Diabetes

Hypertension in Diabetes

Hypertension in Diabetes

Hypertension in Diabetes


Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension in Diabetes provides a comprehensive, state-of-the-art review of key areas related to the epidemiology, pathogenesis, and consequences of hypertension in patients with diabetes. The book discusses the regulation of blood pressure and its specific effects on the heart, kidneys, and retina; it also features various blood pressure treatments and reviews controversies.


The interest in hypertension in diabetes cuts across many specialist disciplines beyond diabetology, including; cardiology, renal medicine, general medicine and therapeutics, among others. As such, much of the information about the epidemiology, pathophysiology, clinical consequences and impact of treatment of hypertension is scattered across many published works. The aim of this book was to bring this information together in a single authoritative and comprehensive compendium.

This has been a greater challenge than I originally envisaged, not least of all because there has recently been an explosion of interest in hypertension in diabetes, fuelled by the emergence of compelling data on the efficacy of antihypertensive therapy in people with diabetes. This challenge has been admirably met by the international panel of authors who agreed to contribute to this book. Their contributions are outstanding. Faced with a constant stream of new data as the manuscripts for the various chapters flowed in, I have had the formidable task of maintaining their high standards in updating their contributions, where necessary, to reflect the emergence of new data and to ensure that upon publication, this book is at the leading edge of current knowledge in this field. In so doing, I acknowledge that the wisdom is theirs and the mistakes are mine! Needless to say, this book does not provide all of the answers to the clinical challenges faced by those treating hypertension in diabetes but I hope it does provide a solid foundation from which to move forward and tackle one of the most important risk factors for premature morbidity and mortality in people with diabetes. The very fact that there is a need for such a book at all reflects how far this area of medicine has moved in the past 10 years. There is much further to go.

I gratefully acknowledge the support of my fellow authors in producing this book, many of whom have remained friends throughout the process! I also acknowledge the patience of the publishers and in particular Alan Burgess, who commissioned the book, and Clive Lawson, whose editorial skills have helped make it happen. Finally, only those who have edited a multi-author medical textbook will recognize the enormity of the sacrifice of time required to complete a project such as this. That sacrifice has inevitably been borne by my wife, Sue, and children, Tom and Amy. Their support, understanding and forbearance are always an inspiration to me and a debt I can never repay. I dedicate this book to them.

Bryan Williams
Leicester, UK

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