Neurobehavioral Plasticity: Learning, Development, and Response to Brain Insults

Neurobehavioral Plasticity: Learning, Development, and Response to Brain Insults

Neurobehavioral Plasticity: Learning, Development, and Response to Brain Insults

Neurobehavioral Plasticity: Learning, Development, and Response to Brain Insults


This book describes a unique combination of research programs based on a striking variety of hypotheses and procedures directed toward understanding the sources and consequences of neurobehavioral plasticity. This remarkable attribute of the nervous system -- to be pliable and capable of being shaped or formed by natural or artificial sources toward adaptation or maladaptation -- is considered in terms of the neurochemical forces and neuroanatomical structure that has been found to be pivotal for this function. The impetus for this volume was a symposium held to honor Robert L. Isaacson for his scientific and pedagogical achievements as well as his contributions to behavioral neuroscience.

Corresponding to his three major research interests, the book is divided into three sections as follows:

• the first explores the relationship between the limbic system and behavior, with an emphasis on learning and memory;

• the second considers -- through a wide range of approaches -- issues of plasticity in behavior and brain; and

• the third deals with neural and chemical determinants of normal and abnormal behavior.

This volume is not only a fitting tribute to Isaacson, but also an unusual collection of new evidence, procedures, and theories destined to have significant influence on behavioral neuroscience.


In association with the 1993 meetings of the International Society for Neurobehavioral Science, a day-long symposium was held to pay tribute to the contributions of Robert L. Isaacsonto behavioral neuroscience. This was not a retirement party. It was instead a meeting of Bob's collaborators in research and former students -- all friends -- with the purpose of sharing data and ideas from research that Bob had inspired in one way or another. In some cases, the inspiration arose from a teacher-student relationship. Others represented joint research efforts and still others resulted from an exchange of ideas in the literature or at past symposia. Unlike an affair to celebrate one's retirement, this symposium reflected the hope and expectation of continued intellectual stimulation from Bob and further discoveries from his productive laboratory.

This book is a collection of papers arising out of this celebration of Bob Isaacson's achievements. A few people were unable to attend this symposium but submitted chapters anyway, whereas others presented papers at the symposium but were unable to submit chapters. The net result was a fine symposium and a set of reports on the cutting edge of theory and technical innovation in behavioral neuroscience.

The book is divided into three parts, which correspond to the three major research interests of Bob Isaacson. Preceding these sections is a chapter by Fred King and Cathy Yarboroughthat illustrates the benefits for human welfare of animal research in behavioral neuroscience. The fascinating history of the Yerkes Regional Primate Center is described in . . .

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