One Renegade Cell: How Cancer Begins

One Renegade Cell: How Cancer Begins

One Renegade Cell: How Cancer Begins

One Renegade Cell: How Cancer Begins


For everyone whose life has been touched by cancer, "One Renegade Cell" tells the story of the search for the ultimate causes of this dreaded disease. 2 line drawings.



Cancer wreaks havoc in almost every part of the human body. Tumors strike the brain and the gut, muscles and bones. Some grow slowly; others are more aggressive and expand quickly. Their presence in human tissues signals chaos and a breakdown of normal function. Cancer brings unwelcome change to a biological machine that is perfect, marvelously beautiful, and complex beyond measure. Wherever tumors appear, they take on the appearance of alien life forms, invaders that enter the body through stealth and begin their programs of destruction from within. But appearances deceive: The truth is much more subtle and endlessly interesting.

Tumors are not foreign invaders. They arise from the same material used by the body to construct its own tissues. Tumors use the same components -- human cells -- to form the jumbled masses that disrupt biological order and function and, if left unchecked, to bring the whole complex, lifesustaining edifice that is the human body crashing down.

How are human tissues put together from single cells? The description above might suggest the involvement of master builders who oversee crews of workers, directing them in the detailed construction of normal and malignant . . .

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