Hydrogen Ion Concentration: Its Significance in the Biological Sciences and Methods for Its Determinations - Vol. 1

Hydrogen Ion Concentration: Its Significance in the Biological Sciences and Methods for Its Determinations - Vol. 1

Hydrogen Ion Concentration: Its Significance in the Biological Sciences and Methods for Its Determinations - Vol. 1

Hydrogen Ion Concentration: Its Significance in the Biological Sciences and Methods for Its Determinations - Vol. 1

Excerpt

When the first edition of this monograph appeared, the circle of those interested in this field was as yet small, and it gives me pleasure to have contributed to the widening of this circle by means of my little book. Since then, in spite of the external difficulties of the years of war, such an enormous amount of work has been performed in this field, that it would be beyond the power of a single individual to render a complete account of all the details. For better or worse I am obliged to sacrifice completeness of the literature and to present the subject in text-book manner. The scope had to be considerably enlarged, so that the second edition is planned in several volumes of which the present first volume comprises the theoretical physico-chemical principles, while the following volumes will present the methodology and the colloid-chemical, physiological and medical applications. In this way a totally new book will appear which has outgrown the scope of its title, and which may be designated as a "second edition" only for the sake of continuity with its small predecessor.

The subject has been covered in the interval in several textbooks of physiology with various degrees of detail. The most notable monographic account is found in the book by W. M. Clark, The Determination of Hydrogen Ions, Baltimore, 1920. This book naturally has had a significant influence upon my second edition, which influence will be evident in the volume on methods.

The present first volume places the fundamental principles of theory upon a wider basis than was done in the corresponding section of the first edition. The cause for this lies in the first place in the broadened realm of pure physical chemistry, and secondly in the extraordinary growth of the multiplicity of applications of this branch to the other branches of science. Therefore I deemed it important to present to my biological readers the general theoretical principles upon a broad foundation, before the details of their application are dealt with.

LEONOR MICHAELIS.

Berlin, Christmas, 1921.

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