Academic journal article The Canadian Journal of Human Sexuality

Sellors, J.W., Karwalajtys, T.L., Kaczorowski, J. et Al. (2003). Incidence, Clearance, and Predictors of Human Papillomavirus Infection in Women. Canadian Medical Association Journal, 168, 421-425

Academic journal article The Canadian Journal of Human Sexuality

Sellors, J.W., Karwalajtys, T.L., Kaczorowski, J. et Al. (2003). Incidence, Clearance, and Predictors of Human Papillomavirus Infection in Women. Canadian Medical Association Journal, 168, 421-425

Article excerpt

Human papillomavirus (HPV) may be the most common sexually transmitted infection in Canada. Some strains of HPV have been clearly linked to cervical intraepithelial neoplasia (CIN) and cervical cancer. Although the incidence of CIN and cervical cancer in Canada is relatively low, especially in comparison to the developing world, determining age specific rates of HPV infection and clearance as well as potential risk factors can further our understanding of the natural history of HPV and help to clarify the potential role of HPV testing in identifying Canadian women in the general population at risk of developing cervical cancer.

The sample for the Sellors et al. study consisted of a sub-sample of Ontario women accessing primary health care who had participated in an earlier HPV prevalence study. The sample for the follow-up study consisted of 253 women who were HPV-negative at baseline and 54 who were HPV-positive. The mean age of participants was 32.7 years and the mean interval between the women's baseline examination and the follow-up was 14.0 months. Cervical soft-brush specimens for testing for carcinogenic HPV types and smears for cytologic examination were taken and the participants completed questionnaires on sexual history and demographic characteristics.

Among women who were HPV-negative at baseline, the highest rate of HPV infection at the follow-up was among women aged 15-19 (25. …

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