Academic journal article The Canadian Journal of Human Sexuality

Epidemiological and Microbiologic Correlates of Chlamydia Trachomatis Infection in Sexual Partnerships

Academic journal article The Canadian Journal of Human Sexuality

Epidemiological and Microbiologic Correlates of Chlamydia Trachomatis Infection in Sexual Partnerships

Article excerpt

Epidemiological and microbiologic correlates of chlamydia trachomatis infection in sexual partnerships. Journal of the American Medical Association, 276, 1737-1742.

Around the world, an estimated 50 million new cases of Chlamydia trachomatis infection occur each year. Chlamydia infections are associated with a spectrum of clinical diseases, including pelvic inflammatory disease, which can lead to infertility and ectopic pregnancy. Previous studies, using culture to detect C trachomatis infection, have suggested that male-to-female transmission is more efficient than female-to-male transmission. However, it may be the case that lower infection rates in males may reflect the possibility that Chlamydia cultures are less sensitive in males than in females.

The primary objective of the Quinn et al. study was to determine the frequency of C trachomatis infection within sexual partnerships by using highly sensitive polymerase chain reaction (PCR) amplification to detect infection. The study sample consisted of 494 sexual partnerships who attended STD clinics in Baltimore, Maryland. Study subjects filled out a questionnaire related to partner-specific sexual and contraceptive practices and other relevant factors. Both partners in each relationship were tested, using both culture and PCR, for C trachomatis.

Using culture, the researchers detected C trachomatis in 12.9% of females and 8. …

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