Academic journal article Bulletin of the World Health Organization

STI Guidelines Address Antimicrobial Resistance

Academic journal article Bulletin of the World Health Organization

STI Guidelines Address Antimicrobial Resistance

Article excerpt

WHO urged countries to update their treatment protocols for sexually-transmitted infections (STI) in response to growing antimicrobial resistance (AMR).

New approaches are urgently needed and possible, given recent advancements in the prevention, diagnosis and treatment of these infections, it said. Effective treatment protocols that take account of global and local resistance patterns are essential to reduce the further development of AMR.

Last month WHO released the first two of several planned sets of treatment guidance on STIs for Neisseria gonorrhoeae and Chlamydia trachomatis. The full set of guidelines on STIs, which updates those from 2003, will be issued in phases over the next couple of years.

N. gonorrhoeae, the bacterium that causes gonorrhoea, has developed high-level resistance to first-line medicines (called quinolones) to treat this infection, and resistance to cephalosporins, another first-line treatment, is also emerging the guideline said.

Quinolones are no longer recommended for the treatment of gonorrhoea due to the reported high-level of resistance. In places, where local resistance data are not available, the new guideline suggests treatment with both ceftriaxone and azithromycin. …

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