Academic journal article Bulletin of the World Health Organization

Yellow Fever Vaccination

Academic journal article Bulletin of the World Health Organization

Yellow Fever Vaccination

Article excerpt

Brazil reported 723 confirmed human cases of yellow fever, including 237 deaths between 1 July 2017 and 28 February 2018 as of 12 March, an increase compared with the 576 confirmed cases, including 184 deaths, reported during the same period a year before.

Yellow fever is an acute viral haem-orrhagic disease transmitted by infected mosquitoes. The increase in the disease is probably due to the virus circulating in densely populated areas, where yellow fever vaccination was not previously recommended.

Since September of last year, when cases of yellow fever in humans, as well as apes were confirmed in Sao Paulo State, Brazil's national authorities have stepped up the vaccination response.

In January, the national authorities launched a vaccination campaign providing fractional and standard doses targeting around 23 million people in three states: Rio de Janeiro, Sao Paulo and Bahia. By the end of February, about 5.5 million of them (23%) had been vaccinated.

Studies show that one fifth of the regular dose provides full immunity against the disease for at least 12 months. Fractional dosing is the recommended strategy to control an outbreak in highly populated areas to avoid vaccine shortages.

Ensuring that everyone who is at risk of yellow fever is vaccinated is one of the goals of the Global Strategy to Eliminate Yellow Fever Epidemics partnership, led by WHO, UNICEF and Gavi, the Vaccine Alliance. …

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