Academic journal article International Journal of Humanities and Peace

Intriguing Leads to Prevent and Treat Cancer

Academic journal article International Journal of Humanities and Peace

Intriguing Leads to Prevent and Treat Cancer

Article excerpt

Researchers are now examining a possible relationship between use of non-steroidal anti-inflammatory drugs (NSAIDS) and a reduction in the risk of colon cancer. In cancers such as Leukemia, Salicylates, a type of NSAID--similar to aspirin may play a role in the battle against cancer.

Dr. A.J. Markowitz of Memorial Sloan Kettering Institute, N.Y., of the gastroenterology and nutrition services tells that NSAIDS may interfere with tumor growth by inhibiting cyclo-oxygenate (COX), a critical enzyme in the production of prostaglandins. Substances that are essential for tumor development are prostaglandins, and that NSAIDS may induce apoptosis (or programmed cell death), in cancer cells.

COX-2 inhibitor--e.g. Celebrex-2, a new class of NSAIDS used for arthritis pain are also being investigated as cancer preventatives at MSK and UCLA.

Herceptin, is a new drug used to treat breast cancer and certain forms of prostate cancer (final stages) in men. Every year, an estimated 184,500 American men develop prostate cancer, and more than 41,000 die from it. The American cancer society considers it the second deadliest type of cancer, after lung cancer.

It is known since 1941 that prostate cancer is stimulated by androgens, or male sex hormones. …

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