Academic journal article Online Journal of Issues in Nursing

Cochrane Review Brief: Cinnamon for Diabetes Mellitus

Academic journal article Online Journal of Issues in Nursing

Cochrane Review Brief: Cinnamon for Diabetes Mellitus

Article excerpt

Keywords: Diabetes Mellitus, Type 1 diabetes, Type 2 diabetes, cinnamon, blood glucose regulation

Review question:

What are the effects of cinnamon in patients with diabetes mellitus?

Nursing Implications:

Long-term control of blood glucose is essential to reduce the risk of developing complications such as retinopathy, neuropathy, nephropathy, cardio-vascular disease and stroke in individuals with diabetes mellitus. Healthcare professionals need to be aware of the risks and benefits of any potential intervention that claims to have the ability to control blood glucose levels, such as cinnamon, especially in the presence of an increasing variety of over the counter products. There is therefore a need to review the available evidence of their effectiveness in diabetes mellitus to inform healthcare policies and practice.

Study Characteristics :

The evidence included in this summary is from a Cochrane systematic review containing 10 prospective, parallel group design randomised controlled trials (RCTs) involving 577 adult participants. All but one study involved participants with a diagnosis of Type 2 diabetes mellitus; the remaining study involved participants with Type 1 diabetes mellitus. The mean age of participants ranged from 52-63 years, with one trial involving adolescents with a mean age of 15 years. The setting was predominantly university outpatient clinics in a range of geographical locations including the USA (4 trials), UK (ltrial), Pakistan (2 trials), Germany (1 trial), Thailand (1 trial) and the Netherlands (1 trial). All studies used monopreparations of cinnamon (primarily Cinnamomum cassia) in tablet or capsule form, at an average daily dose of 2g, for a mean period of 11 weeks. Comparisons consisted of; placebo, no treatment or active medication such as insulin, oral hypoglycaemic agents or other herbal/nutritional preparation. Studies that used combination preparations of cinnamon or failed to meet the criteria for type 1 or type 2 diabetes mellitus were excluded from the review. The primary outcomes of interest focused on fasting blood glucose levels (FBGL); postprandial glucose (PPG) levels; and adverse events with secondary outcomes including Glycosylated haemoglobin Ale (HbAlc); serum insulin; insulin sensitivity; Health-related quality of life (HRQoL); morbidity; and costs. …

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