Academic journal article Iranian Journal of Public Health

Risk Factors Associated with Community-Acquired Tem Producing Klebsiella Pneumonia

Academic journal article Iranian Journal of Public Health

Risk Factors Associated with Community-Acquired Tem Producing Klebsiella Pneumonia

Article excerpt

Background: Antibiotic resistance is one of the major chal- lenges in bacterial infection control. ESBLs-(Extended spec- trum beta lactamases) are the groups of enzymes in which enable the bacteria to become resistant to different types of antibiotics. The aim of this study is to investigate risk factors associated with TEM gene in the Klebsiella pneumoniae isolates which collected from the laboratories of the city.

Methods: The study was a case-control investigation. A case patient was defined as a patient who had one isolate of a TEM gene positive Klebsiella pneumoniae strain. A control pa- tient was defined as a patient who had one isolate of a TEM gene negative Klebsiella pneumoniae strain. TEM gene was de- termined by using double disk diffusion antibiotic suscepti- bility technique and PCR Method.

Results: There were a significant correlation between history of antibiotic use over the past 3 month (OR = 3.68, 95% CI: 1.21-11.19 P<0. …

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