Academic journal article Iranian Journal of Public Health

The Seroepidemiology of Helicobacter Pylori Infection in Tabriz City

Academic journal article Iranian Journal of Public Health

The Seroepidemiology of Helicobacter Pylori Infection in Tabriz City

Article excerpt

Background: Because of the invasiveness of specimen col- lection for bacteriologic diagnosis and the expense of tests such as labeled urea breath tests, serology is the most feasible means of determining the population epidemiology of H. pylori. The aim of this study was to describe the seroepidemi- ology of H. pylori infection in Tabriz city.

Methods: H. pylori-specific ELISA for the presence of IgG antibodies was performed on a representative sample of 21429 (70.02% F, 29.98% M) sera from Tabriz in two years (March 2012 to March 2014), using validated serosurveillance methods. Serum samples were analyzed through qualitative and quantitative methods for anti-H.pylori IgG antibodies with a research use only available enzyme immunoassay kit, that is, ''Anti-H.pylori IgG IBL ELISA". Anti-H.pylori IgG antibody levels greater than 12 U/ml was considered positive. Analysis was conducted usin g SPSS v15.0 and Epi info v3.2.2. The subjects were divided into nine groups according to age, Group I: Children under 10 years old, 1118 subjects, Group II: between 11-20 years old, 1756 subjects (1165 F, 591 M), Group III of between 21-30 years old, 4200 subjects (2976 F, 1224 M), Groups IV: 31-40 years old, 5072 subjects (3576 F, 1505 M), Group V: between 41-50 years old, 4299 subjects (3130 F, 1169 M), Group VI: between 51-60 years old, 3115 subjects (2307 F, 808 M), Groups VII: between 61- 70 years old, 1252 subjects (861 F, 409 M), Group VIII: be- tween 71-80 years old, 483 subjects (284 F, 199 M), Group IX: between 81-90 years old, 116 subjects (64 F, 52 M). …

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