Academic journal article Iranian Journal of Public Health

Increasing Isolation Rate of Mott in South of Turkey

Academic journal article Iranian Journal of Public Health

Increasing Isolation Rate of Mott in South of Turkey

Article excerpt

Background: Mycobacteria other than tuberculosis (MOTT) are environmental organisms capable of causing chronic dis- ease in humans and cause increasingly serious infections es- pecially in immunosuppressive patients. The genus Mycobacte- rium currently has more than 130 species, includes highly infectios M. tuberculosis complex, M. Leprae and new important threat Mycobacterium avium complex (MAC). However all of these cases, the diagnosis of MOTT is often difficult or un- convincing and it cause false diagnosis and treatments.

Methods: The aim of the present study was to describe the diversity of MOTT by sequencing and RFLP of hsp65 gene region and compare these two methods from clinical isolates received to Tropical Disease Center Region Tuberculosis laboratory in Cukurova which has strategical location with border to iraq, syria and Iran. We analyzed 2048 Mycobacterium species from 27.511 clinical materials of 9 different cities total of 19 dispansery and 2 region hospitals patients with between January 2012 - March 2014 in Cukurova region, Turkey. MOTT included in this study were isolated from clinical specimens of 49 patients had pulmonary infection, and 5 infections cases related to other sites (lymphonod, bi- opsy and abscess fluid). MGIT 960 system was used for the recovery of mycobacteria from clinical specimens and MPT64 card test was used for identification. …

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