Academic journal article Iranian Journal of Public Health

The Evaluation of Hepatitis G / C Virus in among HIV Positive Patients and Gbv-C/hgv Affect in the HIV Disease Progression

Academic journal article Iranian Journal of Public Health

The Evaluation of Hepatitis G / C Virus in among HIV Positive Patients and Gbv-C/hgv Affect in the HIV Disease Progression

Article excerpt

Background: Individuals infected with the human immuno- deficiency virus (HIV) are often co-infected with other path- ogens, especially hepatitis viruses. HCV and GBV-C/HGV are blood-borne viruses that are highly prevalent among HIV/AIDS patients. The aims of this study were the evalua- tion of Hepatitis G Virus in among HIV Positive patients and GBV-C/HGV affect in the HIV disease progression.

Methods: One hundred and fifty HIV-infected patients (92 men and 58 women) were included in this study. Patients were categorized into four different high-risk groups: intra- venous drug users (n=48), hemophiliacs (n=45), homosexu- als (n=32) and heterosexuals (n=25). In addition, these pa- tients are separated with history of kidney (n=35), liver (n=60) diseases and history of transfusion (n=55).RNA was extracted from 100 µl of serum or plasma using the RNX plus kit. Detection of GBV-C/HGV-RNA and HCV-RNA were performed using reverse transcription and nested PCR. …

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