Academic journal article Iranian Journal of Public Health

MOLECULAR EPIDEMIOLOGY OF MBL-PRODUCING ACINETOBACTER BAUMANNII IN WESTERN Iran

Academic journal article Iranian Journal of Public Health

MOLECULAR EPIDEMIOLOGY OF MBL-PRODUCING ACINETOBACTER BAUMANNII IN WESTERN Iran

Article excerpt

Background: Carbapenem-resistant A. baumannii has been isolated highly in recent years. Metallo-b-lactamases (MBLs) have been detected and reported from A. baumannii produc- ing carbapenemases in recent times. The aim of this study was to determine both phenotypic and genotyping of MBL producing A. baumannii isolates.

Methods: A total of 110 Acinetobacter spp. were collected from clinical specimens of hospitals in Kermanshah,a west- ern province of Iran. To screen the MBLs, E-test strips (AB Biodisk, Solna, Sweden) were used according to the manufac- turer's instructions. DNA genomic of A. baumannii isolates was SmaI-digested and analyzed by CHEF Mapper PFGE

Results: 89MBL-producing isolates (80.9%) were found using E-test MBL. 68 out of 89 isolates were collected from ICU and 16 isolates from emergency and 5 isolates from children ward. …

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