Academic journal article Iranian Journal of Public Health

The Evaluation of Antibacterial Effect of Methanolic Extract of Curcuma Longa and Zingiber Officinale against Drug-Resistant Acinetobacter Baumannii Isolates from Burn Infection

Academic journal article Iranian Journal of Public Health

The Evaluation of Antibacterial Effect of Methanolic Extract of Curcuma Longa and Zingiber Officinale against Drug-Resistant Acinetobacter Baumannii Isolates from Burn Infection

Article excerpt

Background: Rapid multi drug resistant property of A.baumannii has become a great concern in clinical fields. Due to its resistance to almost all the commercial antibiotic classes in hospitals, searching for a new material has become an important matter. Hence, in this study the antibacterial effect of methanolic extract of Zingiber offinale and Crucu- ma lonaga has been evaluated against drug resistant A. bau- mannii isolates from burn infection.

Methods: 30 drug resistant A.baumannii strains, which were isolated from burn wounds at Motahari hospital of Tehran within 2013, were selected. The plants were purchased from a famous Atari of Tehran and the methanolic extracts of them were prepared by percolator apparatus. Antibacterial activity of the methanolic extract was evaluated by disc diffusion method based on CLSI protocol.

Results: The mean of diameter of the inhibition zone for different concentrations of extracts were; 12.30±6.03 mm at the 400 ppm, 11. …

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