Academic journal article Iranian Journal of Public Health

PREVALENCE OF BLANDM, BLAPER, BLAVEB, BLAIMP AND BLAVIM GENES AMONG ACINETOBACTER BAUMANNII ISOLATED FROM TWO HOSPITALS OF TEHRAN, Iran

Academic journal article Iranian Journal of Public Health

PREVALENCE OF BLANDM, BLAPER, BLAVEB, BLAIMP AND BLAVIM GENES AMONG ACINETOBACTER BAUMANNII ISOLATED FROM TWO HOSPITALS OF TEHRAN, Iran

Article excerpt

Background: The aim of this study was to determine the frequency of blaNDM, blaPER, bla VEB, blaIMP and bla- VIM type genes among A. baumannii isolates from hospital- ized patients in Milad and Loghman Hakim hospitals, Teh- ran-Iran from 2012 to 2013.

Methods: This study was conducted on 108 A. baumannii isolates collected from Milad and Loghman Hakim hospitals in Tehran, Iran. Antibiotic susceptibility tests were performed by Kirby-Bauer disc diffusion and Broth microdilution methods according to CLSI guidelines. The frequency of MBL (metallo-beta-lactamase) and ESBL (extended- spectrum-beta-lactamase) producers were evaluated by CDDT (Combined disk diffusion test). The blaNDM, bla- PER, blaVEB, blaIMP and blaVIM genes were detected by PCR and sequencing methods.

Results: The resistance of A. baumannii isolates tothe tested antibiotics were as follow: 103 (95.4%) to ceftazidime, 108 (100%) to cefotaxime, 105 (95.7%) to cefepime, 99 (91.7%) to imipenem, 99 (91.7%) to meropenem, 87 (80.6%) to ami- kacin, 105 (97.2%) to piperacillin, 100 (92.6%) to ciprofloxa- cin, 103 (95.4%) to piperacillin/tazobactam, 44 (40.7%) to gentamicin, 106 (98.1%) to ampicillin/sulbactam, 106 (98.1%) to co-trimoxazole, 87 (80.6%) to tetracycline and 1 (1.8%) to colistin. Using combined disk diffusion test, it was found that out of 108 cefotaxime-non-susceptible A. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.