Academic journal article Iranian Journal of Public Health

Screening of Actinomycetes from Lipar Area of Gulf of Oman to Research the Antimicrobial Compounds

Academic journal article Iranian Journal of Public Health

Screening of Actinomycetes from Lipar Area of Gulf of Oman to Research the Antimicrobial Compounds

Article excerpt

Background: Actinomycetes are one of the most important sources for producing antimicrobial compounds and the most important prokaryotic microorganisms in this regard. Diversity of antimicrobial compounds isolated from terrestri- al Actinomycetes has been declining and considering the in- creasing resistance of bacteria to antibiotics compounds, searching for new sources is necessary. Marine environment due to its unique characteristics is considered as a good op- tion to search for bacteria with the capability of producing antimicrobial compounds.

Methods: To evaluate the antimicrobial compounds from Actinomycetes, water samples were obtained from the Gulf of Oman (Particularly, from Lipar area). To maximize the isolation of Actinomycetes, the process was done using starch-casein agar, Starch Nitrate Agar and Glycerol Glycine Agar with two different salt concentrations. To investigate the Antimicrobial production activity, the isolated Actinomy- cetes were assessed against reference and pathogenic gram positive strains like Staphylococcus epidermidis, S.intermedius and Methicillin resistant S.aureus and gram negative strains like Pseudomonas, Listeria, Klebsiella, Salmonella, Acinetobacter and E. …

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