Academic journal article Iranian Journal of Public Health

Antimicrobial Resistance in Campylobacter

Academic journal article Iranian Journal of Public Health

Antimicrobial Resistance in Campylobacter

Article excerpt

Background: Most Campylobacter infections are self-limiting but antimicrobial treatment (macrolides, fluoroquinolones) is necessary in severe cases. Rapidly evolving next-generation sequencing technologies may offer beneficial instrument in the future for the prediction of resistance in Campylobacter.

Methods: Pulsed-field gel electrophoresis (PFGE) has been widely used for molecular typing of C. jejuni because of its high discriminatory power. The PCR assay could identify Campylobacter-contaminated samples that were negative using the cultural method, agar dilution and broth microdilution, while a disk diffusion method was recently standardized by the European Committee on Antimicrobial Susceptibility Testing.

Results: Pulsed-field gel electrophoresis (PFGE) method showed that there were several points of cross-contamination of product along the chain, and a high diversity of PFGE types with antimicrobial resistance to ciprofloxacin and tetra- cycline in the retail products. …

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