Academic journal article Iranian Journal of Public Health

The Prevalence of Esbls Producing Pseudomonas Aeruginosa Isolated from Clinical Samples of Khorramabad City

Academic journal article Iranian Journal of Public Health

The Prevalence of Esbls Producing Pseudomonas Aeruginosa Isolated from Clinical Samples of Khorramabad City

Article excerpt

Background: Pseudomonas aeruginosa is among the most important nosocomial bacterial infections with innate resistance to many antibiotics. Broad-spectrum beta-lactamase enzymes areknown as an important cause of the emergence of Pseudomonas aeruginosa drug-resistant isolates. Resistance due to the production of these enzymes in Pseudomonas is rising. These studies have been conducted to find out the prevalence of ESBLs producing enzymes in the Pseudomonas aeruginos in Khorramabad city.

Methods: 70 cases of Pseudomonas aeruginosa were isolated from different samples of patients within a year in Treatment Centers Khorramabad city. Then the isolates were detected by routine biochemical tests were. Antibiotic susceptibility of isolates was assessed using Double Disk Diffusion method. ESBLs producing phenotype among isolated tested using the disc cefotaxime, ceftazidime alone and in combination with Clavulanic acid (Combined Disk Test) was conducted.

Results: Combined disk test results showed that among 70 Pseudomonas aeruginosa isolates, 25 of them were equal to 35. …

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